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:: Volume 28, Issue 5 (12-2020) ::
Journal of Ilam University of Medical Sciences 2020, 28(5): 103-111 Back to browse issues page
Calculation of the Damage Induced by Radionuclide 125I at Different Intervals from the DNA Central Axis based on an Atomic Model using the Geant4-DNA Toolkit
Parvin Ahmadi1 , Mojtaba Shamsaei zafarghandi * 2, Aliasghar Shokri1
1- Dept of Physics, Payame Noor University, Tehran, Iran
2- Faculty of Energy Engineering and Physics, Amirkabir University, Tehran, Iran , pysham@aut.ac.ir
Abstract:   (1109 Views)
Introduction: This study proposed a method to investigate the damage caused by Auger emitter radionuclide radiation.
 
Materials & Methods: This study investigated the detailed rate of breaks induced by iodine radionuclide at different intervals from the DNA center using the Geant4-DNA toolkit and based on the atomic geometric model.
Findings: The mean number of breaks in DNA is shown as a function of distance from the center of the DNA axis to the position of Auger emission radionuclide decay.
 
Discussions & Conclusions: The highest damage occurs by electrons with energies below 1 keV, especially in the proximity of DNA.
Keywords: Auger electron, Double strand break, Geant4-DNA, Radionuclide
Full-Text [PDF 924 kb]   (435 Downloads)    
Type of Study: Research | Subject: biophysics
Received: 2020/06/7 | Accepted: 2020/11/16 | Published: 2020/12/30
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Ahmadi P, Shamsaei zafarghandi M, Shokri A. Calculation of the Damage Induced by Radionuclide 125I at Different Intervals from the DNA Central Axis based on an Atomic Model using the Geant4-DNA Toolkit. Journal of Ilam University of Medical Sciences 2020; 28 (5) :103-111
URL: http://sjimu.medilam.ac.ir/article-1-6600-en.html


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Volume 28, Issue 5 (12-2020) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
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