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:: Volume 28, Issue 6 (1-2021) ::
Journal of Ilam University of Medical Sciences 2021, 28(6): 12-22 Back to browse issues page
Effect of PETTLEP Imagery and Physical Training on the Brain-Derived Neurotrophic Factor and Memory Function in Patients with Multiple Sclerosis
Shahzad Tahmasebi Boroujeni * 1, Mina Ahmadi Kakavandi2 , Seyyed Fardin Qeysari3 , Shahnaz Shahrbanian2
1- Dept of Motor Behaviour and Sport Psychology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran , shahzadtahmaseb@ut.ac.ir
2- Dept of Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehan, Iran
3- Dept of Motor Behaviour and Sport Psychology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
Abstract:   (2439 Views)
Introduction: Physical activity increases serum levels of brain-derived neurotrophic factor (BDNF) in patients with Multiple Sclerosis (MS); however, the effect of learning a skill using mental imagery in the PETTLEP model and comparing its effectiveness with physical activity in the levels of this factor has not been investigated so far. This study aimed to compare the learning of a skill through PETTLEP imagery and physical training. Moreover, it was attempted to investigate the effect of the combination of these two methods on BDNF levels and memory function in MS patients.
 
Materials & Methods: In total, 30 women with MS and a mean age of 37.5±3.02 years Expanded Disability Status Scale (EDSS)=0-2 were included in this study. Based on Kim Karad visual memory test scores, they were divided into three homogeneous groups of 10 subjects per group. The groups included PETTLEP imagery, physical activity, and combined physical training and PETTLEP imagery. Before the intervention, visual memory was assessed using the Kim Karad visual memory test, and BDNF serum concentration by blood sampling method. The groups were subjected to three 30-min sessions weekly (for six weeks). After the intervention, the research variables were reevaluated at the posttest stage. Ethics code: IR.SSRC.REC.1397.012  
 
Findings: The result of one-way ANOVA showed that the combination of PETTLEP imagery exercises and physical training, compared to physical training and imagery alone, increased BDNF levels (P=0.026 and P≤0.0005, respectively). However, imagery training improved memory performance in the short term and long-term memory, compared to physical training (P=0.009 and P=0.034) or combined exercise (P≥0.05).
 
Discussions & Conclusions: Combination of physical training and imagery is effective in the rehabilitation of MS patients, and it can be used as a non-pharmacological method in this regard.
Keywords: Brain-derived neurotrophic factor, Memory, Multiple sclerosis, PETTLEP imagery, Physical activity
Full-Text [PDF 993 kb]   (679 Downloads)    
Type of Study: Research | Subject: Physical Education
Received: 2020/01/25 | Accepted: 2020/09/16 | Published: 2021/02/28
References
1. Raegrant A, Day GS, Marrie RA, Rabinstein A, Cree BA, Gronseth GS, et al. Practice guideline recommendations summary disease modifying therapies for adults with multiple sclerosis report of the guideline development and dissemination and implementation subcommittee of the american academy of neurology. Neurology 2018;90:777-88. doi. 10.1212/WNL.0000000000005347.
2. Sherwood DE. The benefits of random variable practice for spatial accuracy and error detection in a rapid aiming task. Res Quart Exe Sport 1996;67:35-43. doi.10.1080/02701367.1996.10607923
3. George C, Ebers MD. Neurobehavioral aspects of multiple sclerosis. Arch Neurol 1991;48:897. doi.10.1001/archneur.1991.00530210023005
4. Voss MW, Vivar C, Kramer AF. Bridging animal and human models of exercise induced brain plasticity. Trends Cogn Sci 2013;17:525-44. doi. 10.1016/j.tics.2013.08.001.
5. Azoulay D, Vachapova V, Shihman B, Miler A, Karni A. Lower brain derived neurotrophic factor in serum of relapsing remitting MS reversal by glatiramer acetate. J Neuroimmunol 2005;167:215-8. doi.10.1016/j.jneuroim.2005.07.001
6. Frota ERC, Rodrigues DH, Donadi EA, Brum DG, Maciel DRK, Teixeira AL. Increased plasma levels of brain derived neurotrophic factor after multiple sclerosis relapse. Neurosci let 2009;460:130-2. doi.10.1016/j.neulet.2009.05.057.
7. Griffin EW, Mullally S, Foley C, Warmington SA, Omara SM, Kelly AM. Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males. Physiol Behavior 2011;104:934-41. doi.10.1016/j.physbeh.2011.06.005.
8. Zimmermann-Schlatter A, Schuster C, Puhan MA, Siekierka E, Steurer J. Efficacy of motor imagery in post-stroke rehabilitation: a systematic review. J Neuroengine Rehabil 2008;5:8. doi. 10.1186/1743-0003-5-8.
9. Christensen W, Sutton J, Mcilwain DJJM, Language. Cognition in skilled action meshed control and the varieties of skill experience. Mind Lang 2016;31:37-66. doi.10.1111/mila.12094.
10. Wakefield C, Smith D, Moran AP, Holmes P. Functional equivalence or behavioural matching? A critical reflection on 15 years of research using the PETTLEP model of motor imagery. Int Rev Sport Exe Psychol 2013;6:105-21. doi.10.1080/1750984X.2012.724437.
11. Heremans E, D’hooge A-M, De Bondt S, Helsen W, Feys P. The relation between cognitive and motor dysfunction and motor imagery ability in patients with multiple sclerosis. Mul Sclero J 2012;18:1303-9. doi.10.1177/1352458512437812.
12. Holmes P, Collins D. The PETTLEP approach to motor imagery a functional equivalence model for sport psychologists. J Appl Sport Psychol2017; 13:13:60-83. doi.10.1080/10413200109339004.
13. Zich C, Debener S, Schweinitz C, Sterr A, Meekes J, Kranczioch C. High intensity chronic stroke motor imagery neurofeedback training at home three case reports. Clin EEG Neurosci2017;48:403-12. doi.10.1177/1550059417717398
14. Caligiore D, Mustile M, Spalletta G, Baldassarre G. Action observation and motor imagery for rehabilitation in Parkinson's disease a systematic review and an integrative hypothesis. Neurosci Biobehavior Rev 2017;72:210-22. doi.10.1016/j.neubiorev.2016.11.005
15. Hallett M, Iseki K. Real and imaginary gait. Movement Disorders 2012;27(12):1473-4. doi: 10.1002/mds.25186.
16. Ozkul C, Guclugunduz A, Irkec C, Fidan I, Aydin Y, Ozkan T, et al. Effect of combined exercise training on serum brain derived neurotrophic factor suppressors of cytokine signaling 1 and 3 in patients with multiple sclerosis. J Neuroimmunol 2018;316:121-9. doi.10.1016/j.jneuroim.2018.01.002.
17. Wens I, Keytsman C, Deckx N, Cools N, Dalgas U. Brain derived neurotrophic factor in multiple sclerosis effect of 24 weeks endurance and resistance training. European J Neurol 2016;23:1028-35. doi.10.1111/ene.12976
18. Euston DR, Gruber AJ, McNaughton BLJN. The role of medial prefrontal cortex in memory and decision Making. 2012;76:1057-70. doi:10.1016/j.neuron.2012.12.002
19. Vaughan S, Wallis M, Polit D, Steele M, Shum D, Morris N. The effects of multimodal exercise on cognitive and physical functioning and brain derived neurotrophic factor in older women a randomised controlled trial. Age Age2014;43:623-9. doi.10.1093/ageing/afu010
20. Erickson KI, Voss MW, Prakash RS, Basak C, Szabo A, Chaddock L, et al. Exercise training increases size of hippocampus and improves memory. Proce National Acad Sci 2011;108:3017-22. doi.10.1073/pnas.1015950108.
21. Preston AR, Eichenbaum HJCB. Interplay of hippocampus and prefrontal cortex in memory. Cur Biol 2013;23: 764-73. doi.10.1016/j.cub.2013.05.041.
22. Angelucci F, Peppe A, Carlesimo GA, Serafini F, Zabberoni S, Barban F, et al. A pilot study on the effect of cognitive training on BDNF serum levels in individuals with Parkinson disease. Frontiers Hum Neurosci 2015;9:130. doi.10.3389/fnhum.2015.00130.
23. He YY, Zhang XY, Yung WH, Zhu JN, Wang JJ. Role of BDNF in central motor structures and motor diseases. Mole Neurobiol 2013;48:783-93.doi.10.1007/s12035-013-8466-y
24. Woo NH, Lu B. Regulation of cortical interneurons by neurotrophins from development to cognitive disorders. Neuroscientist 2006;12:43-56. doi.10.1177/1073858405284360
25. Sakata K, Martinowich K, Woo NH, Schloesser RJ, Jimenez DV, Ji Y, et al. Role of activity-dependent BDNF expression in hippocampal–prefrontal cortical regulation of behavioral perseverance. Proceedings of the National Academy of Sciences. 2013:201222872. doi: 10.1073/pnas.1222872110
26. Maass A, Duzel S, Brigadski T, Goerke M, Becke A, Sobieray U, et al. Relationships of peripheral IGF-1 and VEGF and BDNF levels to exercise related changes in memory hippocampal perfusion and volumes in older adults. Neuroimage 2016;131:142-54. doi. 10.1016/j.neuroimage.2015.10.084.
27. Volk LJ, Bachman JL, Johnson R, Yu Y, Huganir RLJN. PKM is not required for hippocampal synaptic plasticity learning and memory. Nature 2013;493:420. doi.10.1038/nature11802.
28. Turrigiano GJ. Homeostatic synaptic plasticity local and global mechanisms for stabilizing neuronal function. Cold Spring Harb Per Biol 2012;4:5736. doi: 10.1101/cshperspect.a005736.
29. Madhav T, Pei Q, Zetterström T. Serotonergic cells of the rat raphe nuclei express mRNA of tyrosine kinase B the high affinity receptor for brain derived neurotrophic factor. Mole Brain Res 2001;93:56-63. doi.10.1016/S0169-328X(01)00183-8
30. Krupp LB. Fatigue in multiple sclerosis a guide to diagnosis and management. 1 th ed. Demos Med Publication. 2004;P.114-9.
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Tahmasebi Boroujeni S, Ahmadi Kakavandi M, Qeysari S F, Shahrbanian S. Effect of PETTLEP Imagery and Physical Training on the Brain-Derived Neurotrophic Factor and Memory Function in Patients with Multiple Sclerosis. J. Ilam Uni. Med. Sci. 2021; 28 (6) :12-22
URL: http://sjimu.medilam.ac.ir/article-1-6324-en.html


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Volume 28, Issue 6 (1-2021) Back to browse issues page
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