Introduction: An organization is a network of departments and individuals that improves the performance of the organization through establishing synergy in the meaningful and purposeful communication between departments and individuals. Therefore, effective organizational communication is required to achieve organizational goals. In order to enhance organizational communication in Ilam University of Medical Sciences, the current article investigated the influential factors affecting this communication.
 
Materials & Methods: This descriptive correlational study utilized a researcher-made questionnaire for data collection. The study population included 170 participants selected out of 476 statistical populations (all the staff of Ilam University of Medical Sciences) using simple random sampling. Data were analyzed in SPSS software (version 20) using multiple regression and path analysis.
 
Findings: Based on the results, organizational factor was found to exert a more profound effect on organizational communication in this university with a coefficient of .639, as compared to human factor with a coefficient of 0.258; in other words, the organizational factor is more effective in the enhancement of organizational communication.
 
Discussion & Conclusions: According to the results of this study, Ilam University of Medical Sciences should be looking for an appropriate model of organizational communication and according to its position, design a desirable model in which organizational factors affecting organizational communication should pay more attention.
 

.