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:: Volume 25, Issue 4 (11-2017) ::
Journal of Ilam University of Medical Sciences 2017, 25(4): 141-150 Back to browse issues page
The Comparison of the Effect of Intravenous Acetaminophen with Combination of Suppository Diclofenac and Incisional Bupivacain on the First 24 - Hour Postoperative Pain after Cesarean Section
Arash Farbood1, Solmaz Heidari *2
1- Dept of Anesthesiology, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2- General practitioner, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran , heidarisolmaz@yahoo.com
Abstract:   (4899 Views)

Introduction: The aim of this study was to compare the effect of intravenous acetaminophen with combination of suppository diclofenac and incisional bupivacaine on post cesarean section pain.
 
Materials & methods: This was a double blinded randomized clinical trial study. Patients were randomly allocated to the intravenous acetaminophen group (A) and combination of incisional bupivacaine and diclofenac (B) group. Secondary outcomes included: assessment of the time of first request for analgesic, 24 hr morphine consumption, patient's sleep, sedation score (by Wilson criteria), drug side effects (nausea and vomiting and pruritus) and pain intensity during ambulation and global satisfaction of the patients. Data analysis was done by SPSS software.
 
Findings: There were no significant difference between the mean age and mean weight of groups (p value was 0.15 and 0.41 respectively). During this study, pain score (p<0.001) and morphine sparing effect (p<0.001) in group B was significantly less than group A and in group A patient's  pain started earlier than group B (p<0.001).
 
Discussion & conclusions: We noted that combination of suppository diclofenac and intraincisional bupivacaine could relieve pain better than intravenous acetaminophen and can be used for post cesarean delivery analgesia with more efficacy than intravenous acetaminophen for an opioid-sparing effect. 
 
 

Keywords: Intraincisional bupivacaine, Post-operative pain, Cesarean section
Full-Text [PDF 372 kb]   (1200 Downloads)    
Type of Study: Research |
Received: 2016/04/27 | Accepted: 2016/10/16 | Published: 2017/11/22
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Farbood A, Heidari S. The Comparison of the Effect of Intravenous Acetaminophen with Combination of Suppository Diclofenac and Incisional Bupivacain on the First 24 - Hour Postoperative Pain after Cesarean Section. Journal of Ilam University of Medical Sciences 2017; 25 (4) :141-150
URL: http://sjimu.medilam.ac.ir/article-1-3518-en.html


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Volume 25, Issue 4 (11-2017) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
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