Introduction: Through increased inflammation and oxidative stress, obesity can result in metabolic disorders and other related diseases. Physical activity and consumption of dairy products can be effective in reducing damage. The aim of this study was to determine the effect of eight-week-aerobic exercise and milk consumption on levels of chemerin, resistin and C reactive protein in overweight children.

 Materials & methods: In one Quasi-experimental study 28 healthy obese prepubertal boys (8 to 12 years old) with overweight (95≤BMI≥85) were selected and randomly divided into 4 groups: Exercise, milk, Exercise-milk and Control. Exercise program included 8 weeks (3 sessions per week) with 45 to 60% of maximum heart rate. Milk consumer groups received 236 ml of low-fat cow milk every day. Blood samples were collected before and after the 8 weeks with 14 hours fasting conditions. The data were analyzed using one-way analysis of variance (ANOVA). P<0.05 considered statistically significant. 

Findings: Chemerin, resistin and CRP levels in exercise, exercise-milk and milk groups compared with the control group had a significant decrease. Furthermore combined intervention were associated with significantly greater decreases in this biomarkers compared to other groups (p<0.05).

Discussion & Conclusions: The results of this study showed that the use of non-pharmacological methods such as aerobic training and milk consumption can improve inflammatory markers in overweight children.