Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete Men

Hashemzade ghodaneh, Fateme; Batavani, Mohammad Reza; Ghofrani, Mohsen

doi:10.52547/sjimu.30.3.112

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Volume 30, Issue 3 (8-2022)

Journal of Ilam University of Medical Sciences 2022, 30(3): 112-122

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Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete Men

Fateme Hashemzade ghodaneh¹

, Mohammad Reza Batavani ^*

², Mohsen Ghofrani¹

1- Dept of Exercise Physiology, Faculty of Educational Sciences and Psychology, Sistan and Baluchestan University, Zahedan, Iran
2- Center of Physical Education, Isfahan University of Technology, Isfahan 84156-83111, Iran , batavani@iut.ac.ir

Abstract: (980 Views)

Introduction: Genetic factors affect physical performance, exercise response, as well as elite athletic status; Therefore, the aim of the present study was the investigation of the Frequency and association of SNP rs 8111989 in CKMM A/G gene in weightlifting men with non-athlete men.
Material & Methods: In this descriptive study, the subjects were include of all (n=30) elite male weightlifters (league champions, members of national team, and the champions of Asian, world and Olympics) from Isfahan province, age: 21.77±7.11; Height: 179.87±6.98 and weight: 96.87±22.73 (mean±standard deviation) Which compared with 44 non-athletes with similar anthropometric (age, height and weight) characteristics. 4 cc saliva samples were collected from each subject and After DNA extraction, the allelic and genotypic prevalence of CKMM A/G gene was determined by PCR via RFLP and electrophoresis. Independent t-test, chi-square and logistic regression were used to analyze the data via the SPSS software version 20. Also the significance level was considered at P<0.05.
Findings: The results showed that the prevalence of AG genotype was significantly higher than AA and GG genotypes in weightlifting, non-athlete and total population groups (P <0.05). Also, there was no significant relationship between CKMM A/G genotype and weightlifting status and there was no significant difference between weightlifters and non-athletes (P >0.05).
Discussion & Conclusion: The results showed that the selected Iranian weightlifter, which belongs to the Caucasian race group, has potential genetics in endurance abilities as well as strength / power, likely.

Keywords: Single nucleotide polymorphism, Sport Genomic, Elite Male Weightlifters, Non-athletes

Full-Text [PDF 546 kb] (470 Downloads)

Type of Study: Research | Subject: Physical Education
Received: 2022/01/2 | Accepted: 2022/05/22 | Published: 2022/08/6

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‎ 10.52547/sjimu.30.3.112

‎ 20.1001.1.15634728.1401.30.3.9.2

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Hashemzade ghodaneh F, Batavani M R, Ghofrani M. Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete Men. J. Ilam Uni. Med. Sci. 2022; 30 (3) :112-122
URL: http://sjimu.medilam.ac.ir/article-1-7441-en.html

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