Introduction: Student’s learning is very important in novel education methods. Team-based learning (TBL) is a structured form of cooperative learning, which aims to increase students’ skill of access to higher-level of cognitive learning using individual knowledge in a team. In this study, Physiotherapy and occupational students’ learning was done through the two methods of lecture and TBL for Hand Anatomy.

Materials & methods: This study was carried on 36 Physical therapy and 21 Occupational therapy BS students of rehabilitation school of Tehran university of Medical Sciences in 2002 year. Students’ learning in topics instructed through multiple choice tests in lecture and TBL methods and assessment scores were compared using independent t and one-way ANOVA.

Findings: Students exam scores were increased through TBL in 10.86 percent. Significant difference was observed between lecture and TBL (p≤0/05). A significant correlation was not found between their interest to learn through TBL or lecture.

Discussion & Conclusions: The results showed that TBL method was more successful compared to lecture method. The findings of this study may prove helpful to change the opinion of students, lecturers, and educational managers about the effects of choosing appropriate training methods for knowledge transfer and achieving educational objectives.