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:: Volume 20, Issue 5 (3-2013) ::
Journal of Ilam University of Medical Sciences 2013, 20(5): 255-264 Back to browse issues page
Evaluation of Multi-walled Carbon Nanotubes Cytotoxicity Elements Oxathiazole and Phenyl hydrazine Derivative was prepared by Microwave
S Haydari kashl , H Taher mansori * 1, M Atghaee , E Biazar , F Saifi pour , M Avaz pour , F Kazem begi
1- , h.tahermansuri@iauamol.ac.ir
Abstract:   (51757 Views)
Abstract: introduction: Since carbon nanotubes (CNTs) were discovered by Iijima in 1991, it opened up new opportunities in the field of molecular electronics, sensoring, composite materials, drug delivery system and cancer therapy. Application of CNTs in drug delivery systems is being investigated actively because of their useful combination of size and physicochemical properties. Matherials& Methods: Significant factor in our study, multiwall carbon nanotubes by chemical carboxyl labeled (MWNT-COOH) with methyl 2 - (2 - amino - 4 oxo Thiazole - (H4) - Alidin) acetate ((MWNT-Amide in terms of microwave said. then, carbon nanotubes amide labeled (MWNT-Amide) by reaction with phenyl hydrazine in 20 minutes derived Thiazole on nanotubes produced by spectroscopy IR, Raman, SEM, elemental analysis, and TGA was Also examined the effect of the nanotubes on cells. Finding: Results are highly toxic to cells than other samples of MWNT-Thiazole showed. Discussion & Conclusion: fictionalization of groups is very effective for toxicity reduction of MWNT that can be used for conjugate to drugs or biochemically materials.
Keywords: Nanotubes, Phenyl hydrazine, Microwave, Cytotoxicity
Full-Text [PDF 367 kb]   (5298 Downloads)    
Type of Study: Research | Subject: Medical microbiology
Received: 2013/03/18 | Accepted: 2013/05/13 | Published: 2013/05/13
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haydari kashl S, taher mansori H, atghaee M, biazar E, saifi pour F, avaz pour M et al . Evaluation of Multi-walled Carbon Nanotubes Cytotoxicity Elements Oxathiazole and Phenyl hydrazine Derivative was prepared by Microwave. J. Ilam Uni. Med. Sci. 2013; 20 (5) :255-264
URL: http://sjimu.medilam.ac.ir/article-1-952-en.html

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Volume 20, Issue 5 (3-2013) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
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