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:: Volume 20, Issue 4 (2-2013) ::
Journal of Ilam University of Medical Sciences 2013, 20(4): 252-271 Back to browse issues page
Review of Enterotoxigenic Escherichia coli bacteria vaccines
R Khalesi , J Salimian * 1, Sm Moazeni , F Azizi jalilian
1- , jafarsalimyan@yahoo.com
Abstract:   (13650 Views)
Enterotoxigenic Escherichia coli is the most common bacterial agent producing diarrhea in the world wide. This bacterium includes some virulence factors such as colonization factors and heat-labile toxin and/ or heat-stable toxin. Enterotoxigenic Escherichia coli attached to the intestinal epithelial cell surface through CFs and causes diarrhea by toxin secretion. Molecular pathogenesis stu-dies demonstrate that there are many pro-phylactic approaches for this infection. The best possible way is designing and prod-ucing efficient vaccine that enabeling to induc protective immunity against the most of bacterial strains. Vaccine candidate molecule(s) that are used to design a vaccine, in addition to possess immuno-genicity and safety they should be wid-espread among variety of strains and co-ntain conserved and common epitops. This article pays attention to review some infor-mation and results of conducted researches on enterotoxigenic Escherichia coli vaccine and importance of the bacteria and its pathogenesis.
Keywords: enterotoxigenic escherichia coli, pathogenesis, vaccine, virulence factors
Full-Text [PDF 371 kb]   (19143 Downloads)    
Type of Study: Research | Subject: Medical microbiology
Received: 2013/03/17 | Accepted: 2013/10/15 | Published: 2013/10/15
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khalesi R, salimian J, moazeni S, azizi jalilian F. Review of Enterotoxigenic Escherichia coli bacteria vaccines. J. Ilam Uni. Med. Sci. 2013; 20 (4) :252-271
URL: http://sjimu.medilam.ac.ir/article-1-920-en.html

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Volume 20, Issue 4 (2-2013) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
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