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:: Volume 32, Issue 6 (2-2025) ::
Journal of Ilam University of Medical Sciences 2025, 32(6): 128-140 Back to browse issues page
The Effect of Intermittent High-Intensity and Continuous Moderate-Intensity Exercises on CTRP-1, CTRP-5 and CTRP-15 Values in Rats Fed with a High-Fat Diet
Mostafa Fahmi Alsediri1 , Keyvan Sharifmoradi * 2, Mousa Khalafi1 , Zahra Pezeshki3
1- Dept of Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran
2- Dept of Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran , ksharifmoradi@gmail.com
3- Dept of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract:   (13 Views)
Introduction:  The effect of high-intensity interval training and moderate-intensity continuous training on CTRPs under dietary Intake is unclear. So, the aim of the present study was to investigate the effect of high-intensity interval training (HIIT) and moderate intensity continuous training (MICT) on protein levels of CTRP-1, CTRP-5, and CTRP-15 in rats fed a high-fat diet.
Materials & Methods: This study was experimental in nature, utilizing a post-test design with a control group. Twenty-four male Wistar rats were randomly divided into four equal groups, including standard diet (6), high-fat diet (6), high-fat diet with high-intensity interval training (6), and high-fat diet with moderate intensity continuous training (6). The HIIT and MICT groups did their own group-specific exercise for 8 weeks, 5 sessions per week. To measure the protein levels of CTRP-1, CTRP-5, and CTRP-15 using the western blot method. were used. Statistical analysis was performed using SPSS V.26; one-way analysis. of variance and Tukey's post hoc test were used to analyze data at a significance level less than 0.05.
Results: In the HFD group, visceral fat levels of CTRP-1, CTRP-5, and CTRP-15 went up significantly (P<0.001) after eight weeks of the diet. A lot less CTRP-1, CTRP-5, and CTRP-15 visceral fat was found in the MICT group compared to the HFD group (P<0.001). The HIIT protocol also greatly lowered the amount of CTRP-1 protein in visceral fat compared to the ND group (P=0.001).
Conclusion: While exercise training can prevent the effects of a high-fat diet, moderate-intensity exercise training is a more effective approach. A high-fat diet is associated with a significant increase in CTRPs of visceral fat.
Keywords: High-fat diet, Exercise training, Visceral fat, CTRP-1, CTRP-5, CTRP-15
Full-Text [PDF 821 kb]   (9 Downloads)    
Type of Study: Research | Subject: Physical Education
Received: 2024/06/19 | Accepted: 2024/10/23 | Published: 2025/02/3
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Alsediri M F, Sharifmoradi K, Khalafi M, Pezeshki Z. The Effect of Intermittent High-Intensity and Continuous Moderate-Intensity Exercises on CTRP-1, CTRP-5 and CTRP-15 Values in Rats Fed with a High-Fat Diet. J. Ilam Uni. Med. Sci. 2025; 32 (6) :128-140
URL: http://sjimu.medilam.ac.ir/article-1-8306-en.html


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Volume 32, Issue 6 (2-2025) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
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