Investigation of Causes and Risk Factors for Gastrointestinal Bleeding (GIB) in Patients Referring to Shahid Mostafa Khomeini Hospital, Ilam City, from 2014 to 2019

Seidkhani, Hossein; Barkhordarian Abadeh, Azadeh; Mami, Masoud

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Volume 31, Issue 3 (8-2023)

Journal of Ilam University of Medical Sciences 2023, 31(3): 9-19

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Investigation of Causes and Risk Factors for Gastrointestinal Bleeding (GIB) in Patients Referring to Shahid Mostafa Khomeini Hospital, Ilam City, from 2014 to 2019

Hossein Seidkhani ^*

¹, Azadeh Barkhordarian Abadeh²

, Masoud Mami²

1- Dept of Biostatistics, School of Public Health, Ilam University of Medical Sciences, Ilam, Iran , hseidkhani@gmail.com
2- Dept of Internal Medicine, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran

Abstract: (740 Views)

Introduction: Gastrointestinal bleeding (GIB) is one of the most important diseases in internal medicine, which can occur due to bleeding in any of the gastrointestinal organs. The best diagnostic method for identifying the source of bleeding in patients is endoscopy and colonoscopy. Therefore, this study was conducted to determine the causes and the most common risk factors for GIB in patients referring to Shahid Mustafa Khomeini Hospital in Ilam.
Material & Methods: In this retrospective analytical study, all patients with clear gastrointestinal bleeding symptoms, including melena, hematemesis, hematochezia, and passing clots, who referred to Shahid Mustafa Khomeini Hospital in Ilam from 2014 to 2019, were evaluated. The demographic information of the patients, their medical history, and the description of the medications they were taking, which were recorded in their medical records, were entered into the questionnaire form. Data analysis was performed using descriptive and inferential statistical methods.
Findings: In this study, 650 patients with an average age of 57.24 years, ranging from 19 to 99 years, were included. The majority of patients were in the older age group (above 60 years) and were male. The most common complaint among patients was hematemesis (41.4%), while anemia was the least common complaint (1.8%). The most common causes of gastrointestinal bleeding in both genders were peptic ulcer, gastric mass, and esophageal varices. There was a significant correlation between age and gastrointestinal bleeding symptoms (p < 0.05). Gastrointestinal bleeding symptoms, including hematemesis, melena, and rectorrhagia, were more common in men and in smokers. Alcohol consumption also had an impact on the occurrence of gastrointestinal bleeding with hematemesis, melena, and rectorrhagia.
Discussion & Conclusion: Endoscopy and colonoscopy are the best diagnostic methods for patients with gastrointestinal bleeding. Therefore, this study was conducted to determine the causes and the most common risk factors for GIB in patients referring to Shahid Mustafa Khomeini Hospital in Ilam from 2014 to 2019. The findings of this study can help improve the diagnosis and management of gastrointestinal bleeding in these patients.

Keywords: Gastrointestinal Hemorrhage (GIB), Risk Factors, Etiology, Hemorrhage, Digestive System Diseases

Full-Text [PDF 627 kb] (431 Downloads)

Type of Study: Research | Subject: gastrointestinal and hepatic
Received: 2022/08/1 | Accepted: 2023/05/2 | Published: 2023/09/6

References

1. Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL. Harrison's principles of internal medicine: McGraw Hill; 2001.

2. Olokoba AB, Obateru OA, Bojuwoye MO, Olatoke SA, Bolarinwa OA, Olokoba LB. Indications and findings at colonoscopy in Ilorin, Nigeria. Niger Med J 2013;54:111-4. doi: 10.4103/0300-1652.110044.

3. Zuckerman DA, Bocchini TP, Birnbaum EH. Massive hemorrhage in the lower gastrointestinal tract in adults: diagnostic imaging and intervention. AJR Am J Roentgenol 1993;161:703-11. doi: 10.2214/ajr.161.4.8372742.

4. Geiger TM, Miedema BW, Geana MV, Thaler K, Rangnekar NJ, Cameron GT. Improving rates for screening colonoscopy: Analysis of the health information national trends survey (HINTS I) data. Surg Endosc 2008;22:527-33. doi: 10.1007/s00464-007-9673-2.

5. Massey AC. Microcytic anemia. Differential diagnosis and management of iron deficiency anemia. Med Clin North Am 1992;76:549-66. doi: 10.1016/s0025-7125(16)30339-x.

6. Gado AS, Ebeid BA, Abdelmohsen AM, Axon AT. Clinical outcome of acute upper gastrointestinal hemorrhage among patients admitted to a government hospital in Egypt. Saudi J Gastroenterol 2012;18:34-9. doi: 10.4103/1319-3767.91737.

7. Ray-Offor E, Elenwo SN. Endoscopic Evaluation of Upper and Lower Gastro-Intestinal Bleeding. Niger J Surg 2015;21:106-10. doi: 10.4103/1117-6806.162575.

8. Trawick EP, Yachimski PS. Management of non-variceal upper gastrointestinal tract hemorrhage: controversies and areas of uncertainty. World J Gastroenterol 2012;18:1159-65. doi: 10.3748/wjg.v18.11.1159.

9. Longstreth GF. Epidemiology of hospitalization for acute upper gastrointestinal hemorrhage: a population-based study. Am J Gastroenterol 1995;90:206-10.

10. Boonpongmanee S, Fleischer DE, Pezzullo JC, Collier K, Mayoral W, Al-Kawas F, et al. The frequency of peptic ulcer as a cause of upper-GI bleeding is exaggerated. Gastrointest Endosc 2004;59:788-94. doi: 10.1016/s0016-5107(04)00181-6.

11. Gralnek IM, Dulai GS. Incremental value of upper endoscopy for triage of patients with acute non-variceal upper-GI hemorrhage. Gastrointest Endosc 2004;60:9-14. doi: 10.1016/s0016-5107(04)01524-x.

12. Kahi CJ, Jensen DM, Sung JJ, Bleau BL, Jung HK, Eckert G, et al. Endoscopic therapy versus medical therapy for bleeding peptic ulcer with adherent clot: a meta-analysis. Gastroenterology 2005;129:855-62. doi: 10.1053/j.gastro.2005.06.070.

13. Barkun A, Bardou M, Marshall JK. Nonvariceal Upper GI Bleeding Consensus Conference Group. Consensus recommendations for managing patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med2003;139:843-57. doi: 10.7326/0003-4819-139-10-200311180-00012.

14. Lo CC, Hsu PI, Lo GH, Lin CK, Chan HH, Tsai WL, et al. Comparison of hemostatic efficacy for epinephrine injection alone and injection combined with hemoclip therapy in treating high-risk bleeding ulcers. Gastrointest Endosc 2006;63:767-73. doi: 10.1016/j.gie.2005.11.048.

15. Nozari N. Incidence of endoscopic findings and related risk factors in patients with gastrointestinal bleeding after percutaneous coronary intervention and combination antiplatelet therapy. Govaresh 2016;21:98-103.(persian)

16. Baghbanian M, Salmanroghani H, Mofidi Naiini M, Amirbeigy M, Rezvaninejad S, Akhondi M. Etiology of Lower Gastrointestinal Bleeding in Patients Less than 40 Years Old, Yazd, Iran. JSSU 2018;25:970-8.

17. Hreinsson JP, Gumundsson S, Kalaitzakis E, Björnsson ES. Lower gastrointestinal bleeding: incidence, etiology, and outcomes in a population-based setting. Eur J Gastroenterol Hepatol 2013;25:37-43. doi: 10.1097/MEG.0b013e32835948e3.

18. Sherid M, Sulaiman S, Samo S, Husein H, Tupper R, Spurr C, Sifuentes H, Sridhar S. Risk of Gastrointestinal Bleeding with Rivaroxaban: A Comparative Study with Warfarin. Gastroenterol Res Pract 2016;2016:9589036. doi: 10.1155/2016/9589036.

19. Jiang Y, Li Y, Xu H, Shi Y, Song Y, Li Y. Risk factors for upper gastrointestinal bleeding requiring hospitalization. Int J Clin Exp Med 2016;9:4539-44.

20. Lei TX, MN S, XY. L. Upper gastrointestinal bleeding in elderly patients: An analysis of210 cases. World Chin J Dig 2012;20: 3164-6.

21. Dagher L, Burroughs A. Variceal bleeding and portal hypertensive gastropathy. Eur J Gastroenterol Hepatol 2001;13:81-8. doi: 10.1097/00042737-200101000-00017.

22. Ghanadi K, Anbari K, Zendedel A, Abdolahian M, Mohammad TZ. Risk factors for upper gastrointestinal bleeding in patients referred to the Shohada Ashayer Khoramabad in 2011. JBUMS2012;19.(persian)

23. Lenti MV, Pasina L, Cococcia S, Cortesi L, Miceli E, Caccia Dominioni C, et al. Mortality rate and risk factors for gastrointestinal bleeding in elderly patients. Eur J Intern Med 2019;61:54-61. doi: 10.1016/j.ejim.2018.11.003.

24. Moledina SM, Komba E. Risk factors for mortality among patients admitted with upper gastrointestinal bleeding at a tertiary hospital: a prospective cohort study. BMC Gastroenterol 2017;17:165. doi: 10.1186/s12876-017-0712-8.

25. Sugawa C, Steffes CP, Nakamura R, Sferra JJ, Sferra CS, Sugimura Y, Fromm D. Upper GI bleeding in an urban hospital. Etiology, recurrence, and prognosis. Ann Surg 1990;212:521-6; discussion 526-7. doi: 10.1097/00000658-199010000-00014.

26. Brzozowski T, Konturek PC, Konturek SJ, Brzozowska I, Pawlik T. Role of prostaglandins in gastroprotection and gastric adaptation. J Physiol Pharmacol 2005;56 Suppl 5:33-55.

27. McCarthy D. Nonsteroidal anti-inflammatory drug-related gastrointestinal toxicity: definitions and epidemiology. Am J Med 1998;105:3S-9S. doi: 10.1016/s0002-9343(98)00274-5.

28. Laine L, Takeuchi K, Tarnawski A. Gastric mucosal defense and cytoprotection: bench to bedside. Gastroenterology 2008;135:41-60. doi: 10.1053/j.gastro.2008.05.030.

29. G. Z. Analysis on Etiology, causes, endoscopic treatment timing and methods of acutenon-variceal upper gastrointestinal Bleeding. JiLin University. 2014.

30. Martínek J, Hlavova K, Zavada F, Seifert B, Rejchrt S, Urban O, et al. "A surviving myth"--corticosteroids are still considered ulcerogenic by a majority of physicians. Scand J Gastroenterol 2010;45:1156-61. doi: 10.3109/00365521.2010.497935.

31. Narum S, Westergren T, Klemp M. Corticosteroids and risk of gastrointestinal bleeding: a systematic review and meta-analysis. BMJ Open2014;4:e004587. doi: 10.1136/bmjopen-2013-004587.

32. Mousavi S, Toussy J, Zahmatkesh M, Fatemi R, Babaei M, Rabizadeh M. Evaluation of Change in Etiology and Epidemiology of Upper GI Bleeding in A Population Study. Govaresh 2006;11:80-5.(persian).

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Seidkhani H, Barkhordarian Abadeh A, Mami M. Investigation of Causes and Risk Factors for Gastrointestinal Bleeding (GIB) in Patients Referring to Shahid Mostafa Khomeini Hospital, Ilam City, from 2014 to 2019. J. Ilam Uni. Med. Sci. 2023; 31 (3) :9-19
URL: http://sjimu.medilam.ac.ir/article-1-7669-en.html

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