Evaluation of the Patients’ Conditions with Respiratory Tract Infections and Interventions to Prevent Taking Antibiotics in these Patients

Sadeghifard, Nourkhoda; Ghafourian, Sobhan; Mohamadi, Jasem; Nazari, Ali; Shahmari, Mahtab; Pakzad, Reza; Valadbeigi, Hassan

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Volume 31, Issue 1 (4-2023)

Journal of Ilam University of Medical Sciences 2023, 31(1): 42-51

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Evaluation of the Patients’ Conditions with Respiratory Tract Infections and Interventions to Prevent Taking Antibiotics in these Patients

Nourkhoda Sadeghifard¹

, Sobhan Ghafourian²

, Jasem Mohamadi³

, Ali Nazari⁴

, Mahtab Shahmari⁵

, Reza Pakzad⁶

, Hassan Valadbeigi ^*

⁷

1- Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran
2- Dept of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
3- Dept of Pediatrics, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
4- Dept of Infectious Disease, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
5- Food and Drugs Administration, Ilam University of Medical Sciences, Ilam, Iran
6- Dept of Epidemiology, Faculty of Health, Ilam University of Medical sciences, Ilam, Iran
7- Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran , hasan.valadbeigi@gmail.com

Abstract: (911 Views)

Introduction: Overuse and inappropriate antibiotic prescription for acute respiratory infections (ARIs) are among the major contributors to the current antibiotic resistance problem. ARIs are among the most common infections, and due to their high prevalence, they are of great importance and can play a vital role in mortality among children and adults. Therefore, this study aimed to train physicians in terms of communication skills with patients to reduce the use of antibiotic, which results in minimizing antibiotic resistance, proper use of antibiotics when it is necessary to use, and minimize self-medication, which ultimately leads to reducing costs.
Material & Methods: This cross-sectional study was conducted to control antibiotic consumption in patients with respiratory infections referring to physicians.
(Ethic Code: IR.Medilam.Rec.1395.112)
Findings: The results of this study showed that cefixime and co-amoxiclav antibiotics were the least and the most prescribed by gastroenterologists and hepatologists, as well as pediatricians, respectively. In addition, according to the results, cefixime antibiotic showed statistically significant results (P<0.05).
Discussion & Conclusion: The results revealed a reduction in the prescriptions of cefixime and amoxicillin by general physicians, amoxicillin, cefixime, and azithromycin by pediatricians, and co-amoxiclav by infectious disease specialists. However, there was an increase in antibiotic prescriptions by gastroenterologists and hepatologists which could lead to resistance increase, and consequently, the treatment failure. Accordingly, it is of necessary importance to take measures and implement instructions for logical prescription of antibiotics leading to infection control, reducing antibiotic resistance, reducing the length of patients’ hospital stay, as well as mortality due to infection, and reducing treatment costs for patients and hospitals.

Keywords: Antibiotics prescription, Intervention, Respiratory infection, Physician prescriptions

Full-Text [PDF 1276 kb] (553 Downloads)

Type of Study: Research | Subject: Bacteriology
Received: 2022/07/11 | Accepted: 2022/10/16 | Published: 2023/04/4

References

1. Goossens H, Ferech M, Vander Stichele R, Elseviers M, Group EP. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005;365:579-87. doi: 10.1016/S0140-6736(05)17907-0.

2. Little P, Moore M, Kelly J, Williamson I, Leydon G, McDermott L, et al. Delayed antibiotic prescribing strategies for respiratory tract infections in primary care: pragmatic, factorial, randomised controlled trial. BMJ 2014;348. doi:10.1136/bmj.g1606.

3. Spurling GK, Del Mar CB, Dooley L, Clark J, Askew DA. Delayed antibiotic prescriptions for respiratory infections. Cochrane Database Syst Rev 2017:9. doi:10.1002/14651858.CD004417.pub5.

4. Nazari Z, Tabarraei E, Akbarmehr J. Molecular Epidemiology of Adenoviruses among Respiratory Infected Patients. Med Lab J 2014;8:1-6.

5. Murarkar S, Gothankar J, Doke P, Dhumale G, Pore PD, Lalwani S, et al. Prevalence of the acute respiratory infections and associated factors in the rural areas and urban slum areas of western Maharashtra, India: a community-based cross-sectional study. Front Public Health 2021; 9:723807 .doi: 10.3389/fpubh.2021.723807 .

6. Al-Tawfiq JA, Zumla A, Gautret P, Gray GC, Hui DS, Al-Rabeeah AA, et al. Surveillance for emerging respiratory viruses. Lancet Infect Dis 2014;14:992-1000.doi:10.1016/S1473-3099(14)70840-0.

7. Zumla A, Memish ZA, Maeurer M, Bates M, Mwaba P, Al-Tawfiq JA, et al. Emerging novel and antimicrobial-resistant respiratory tract infections: new drug development and therapeutic options. Lancet Infect Dis 2014;14:1136-49.doi: 10.1016/S1473-3099(14)70828-X .

8. Di Mario S, Gagliotti C, Buttazzi R, Marchetti F, Dodi I, Barbieri L, et al. Reducing antibiotic prescriptions in children is not associated with higher rate of complications. Eur J Pediatr 2021;180:1185-92.doi: 10.1007/s00431-020-03861-8.

9. Hussain A, AARØ LE, KVÅLE G. Impact of a health education program to promote consumption of vitamin A rich foods in Bangladesh. Health Promot Int 1997:103-9.doi: 10.1093/heapro/12.2.103.

10. Tembo KC. Grass-root health education strategies in Malawi. R Soc Health J 1995;115:318-9. doi: 10.1177/146642409511500512

11. Piltcher OB, Kosugi EM, Sakano E, Mion O, Testa JRG, Romano FR, et al. How to avoid the inappropriate use of antibiotics in upper respiratory tract infections? A position statement from an expert panel. Braz J Otorhinolaryngol 2018;84:265-79.doi: 10.1016/j.bjorl.2018.02.001 .

12. Andrews T , Thompson M, I Buckley D, Heneghan C, Deyo R, Redmond N, et al. Interventions to influence consulting and antibiotic use for acute respiratory tract infections in children: a systematic review and meta-analysis. PLoS One 2012;7:e30334. doi: 10.1371/journal.pone.0030334.

13. Bennett J, Dolin R, Blaser M. Principles and practice of infectious diseases, vol 1 Elsevier Health Sciences. Philadelphia 2014.ISBN:97804710344896.

14. Black RE, Cousens S, Johnson HL, Lawn JE, Rudan I, Bassani DG, et al. Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet 2010;375:1969-87.doi: 10.1016/S0140-6736(10)60549-1 .

15. Abd-Jamil J, Teoh B-T, Hassan EH, Roslan N, AbuBakar S. Molecular identification of adenovirus causing respiratory tract infection in pediatric patients at the University of Malaya Medical Center. BMC Pediatr 2010;10:1-7. doi: 10.1186/1471-2431-10-46.

16. Rautakorpi UM, Huikko S, Honkanen P, Klaukka T, Mäkelä M, Palva E, et al. The Antimicrobial Treatment Strategies (MIKSTRA) program: a 5-year follow-up of infection-specific antibiotic use in primary health care and the effect of implementation of treatment guidelines. Clin Infect Dis 2006;42:1221-30. doi: 10.1086/503036 .

17. Aoybamroong N, Kantamalee W, Thadanipon K, Techasaensiri C, Malathum K, Apiwattanakul N. Impact of an antibiotic stewardship program on antibiotic prescription for acute respiratory tract infections in children: A prospective before-after study. Clin Pediatr 2019;58:1166-74.doi: 10.1177/0009922819870248.

18. van der Velden AW, Kuyvenhoven MM, Verheij TJ. Improving antibiotic prescribing quality by an intervention embedded in the primary care practice accreditation: the ARTI4 randomized trial. J Antimicrob Chemother 2016;71:257-63. doi: 10.1093/jac/dkv328.

19. Oliveira I, Rego C, Semedo G, Gomes D, Figueiras A, Roque F, et al. Systematic review on the impact of guidelines adherence on antibiotic prescription in respiratory infections. Antibiotics 2020;9:546. doi: 10.3390/antibiotics9090546.

20. Yoon YK, Park CS, Kim JW, Hwang K, Lee SY, Kim TH, et al. Guidelines for the antibiotic use in adults with acute upper respiratory tract infections. Infect Chemother 2017;49:326-52.doi: 10.3947/ic.2017.49.4.326 .

21. Wong DM, Blumberg DA, Lowe LG. Guidelines for the use of antibiotics in acute upper respiratory infections. Am Fam Physician 2006;74:956-66.

22. Esfahani BN, Basiri R, Mirhosseini SMM, Moghim S, Dolatkhah S. Nosocomial infections in intensive care unit: pattern of antibiotic-resistance in Iranian community. Ad Biomed Res 2017;6. doi: 10.4103/2277-9175.205527 .

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Sadeghifard N, Ghafourian S, Mohamadi J, Nazari A, Shahmari M, Pakzad R et al . Evaluation of the Patients’ Conditions with Respiratory Tract Infections and Interventions to Prevent Taking Antibiotics in these Patients. J. Ilam Uni. Med. Sci. 2023; 31 (1) :42-51
URL: http://sjimu.medilam.ac.ir/article-1-7645-en.html

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