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:: Volume 30, Issue 2 (6-2022) ::
Journal of Ilam University of Medical Sciences 2022, 30(2): 1-7 Back to browse issues page
Antimicrobial Effects of Aqueous-Alcoholic Extract of Artemisia Turanica against Methicillin-Resistant Staphylococcus aureus (MRSA): An in vitro Study
Hasan Bagheri yazdi * 1, Hamed Norouzi taheri2
1- Farhangian University ,Iran , bagheriyazdi@cfu.ac.ir
2- Farhangian University, Mashhad, Iran.
Abstract:   (1517 Views)
Introduction: Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are on the rise worldwide. Over the last few decades, new compounds of natural origins have regained interest as an alternative to antibiotics in the treatment of MRSA infections. This study aimed to investigate the antimicrobial effects of Artemisia Turanica extract, a native plant of Iran.
Material & Methods: The plant was subjected to aqueous-alcoholic extraction, and its antibacterial effects were then evaluated using the disk diffusion method. All tests were performed in triplicate, and the mean diameter of the growth inhibition zone was recorded. Finally, the minimum inhibitory concentrations and minimum bactericidal concentrations (MIC and MBC) against MRSA were determined using the micro broth dilution method.
(Ethic code: IR.MUMS.REC.1401.015)
Findings: The recorded antimicrobial activity against MRSA of the plant extract (29±1.5) was higher than that of the vancomycin antibiotic (14±1.4). The effect of MIC on MRSA was recorded at 98 μg/mL, and the MBC was estimated at 157 μg/mL. The plant extract also showed antifungal activity against the tested pathogenic fungal strains.
Discussion & Conclusion: Artemisia Turanica extract has a strong antibacterial activity against MRSA. Accordingly, the purification and identification of active compounds of this extract on an industrial scale pave the way for introducing new antimicrobial compounds.
 
Keywords: Antibacterial effect, Drug resistance, MRSA, Plant extract
Full-Text [PDF 1158 kb]   (783 Downloads)    
Type of Study: Research | Subject: Natural Resources
Received: 2021/07/2 | Accepted: 2022/01/9 | Published: 2022/06/5
References
1. Mozaffarian V. Compositae (Anthemideae & Ehinopeae) no. 59. Tehran: Research Institute of Forest and Rangelands. Flora of Iran. 2008; pp. 199–261.
2. Emami S, Aghazari F. Iranian endemic phanerogams. Iran J Pharma Res 2010; 3: 62-63.
3. Ashrafpour M, Rezaei H, Sefidgar A, Baradaran M, Sharifi H. Survey of the Antibacterial Properties of Aqueous Ethanolic and Methanolic Extraction of Artemisia Annua Around the City of Babol. J Ilam Uni Med Sci 2016; 23:129-141
4. Tan RX, Tang HQ, Hu J, Shuai B. Lignans and sesquiterpene lactones from Artemisia sieversiana and Inula racemosa. Phytochemistry 1998; 49:157–161. doi: 10.1016/s0031-9422(97)00889-3.
5. Bora KS, Sharma A. The genus Artemisia: a comprehensive review. Pharm Biol 2011; 49:101-9. doi: 10.3109/13880209.2010.497815
6. Ellis MD, Baxendale FP. Toxicity of seven monoterpenoids to tracheal mites (Acari: Tarsonemidae) and their honey bee (Hymenoptera: Apidae) hosts when applied as fumigants. J Econ Entomol 1997; 90:1087–91. doi:10.1093/jee/ 90.5.1087.
7. Al-Haj NA, Mashan NI, Shamsudin MN, Mohamad H, Vairappan CS, Sekawi Z. Antibacterial activity in marine algae Eucheumad enticulatum against Staphylococcus aureus and Streptococcus pyogenes. Res J Biol Sci 2009;4: 519-24. doi: rjbsci.2009.519.524.
8. Shopsin B, Kreiswirth BN. Molecular epidemiology of methicillin-resistant Staphylococcus aureus. Emerg Infect Dis 2001;7: 323-6. doi: 10.3201/ eid0702.010236.
9. Kluytmans J, van Belkum A, Verbrugh H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev 1997;10: 505-20. doi: 10.1128/ CMR.10.3.505.
10. Bataineh S, Tarazi YH, Ahmad WA. Antibacterial efficacy of some medicinal plants on multidrug resistance bacteria and their toxicity on Eukaryotic cells. Appl Sci 2021;11, 8479. doi.org/10.3390/ app11188479
11. Dulger B, Gonuz A. Antimicrobial activity of certain plants used in Turkish traditional medicine. Asian J Plant Sci 2004; 3: 104-7. doi:10.3923/ ajps.2004.104.107
12. Murphy Cowan M. Plant Products as Antimicrobial Agents. Clin Microbiol Rev 1999; 12:564-82. doi: 10.1128/CMR.12.4.564
13. Norouzi H, Rabbani khorasgani M, Danesh A. Anti-MRSA activity of a bioactive compound produced by a marine Streptomyces and its optimization using statistical experimental design. Iran J Basic Med Sci 2019; 22:1073-1084. doi: 10.22038/ijbms.2019.33880.8058
14. Andrews J. for the BSAC Working Party on Susceptibility Testing, BSAC standardized disc susceptibility testing method (version 7). J Antimicrob Chemother 2008; 62:256-78. doi: 10.1093/jac/dkn194
15. Nostro A, Ger MP, Angelo VD, Cannatelli MAC. Extractionmethods and biouautography for evallution plant antimicrobial activity. Applied Microbiol 2000; 15:379-85. doi: 10.1046/j.1472-765x.2000.00731.x.
16. Salar Bashi D, Attaran Dowom S, Fazly Bazzaz BS, Khanzadeh F, Soheili V, Mohammadpour A. Evaluation, prediction and optimization the ultrasound-assisted extraction method using response surface methodology: antioxidant and biological properties of Stachys Parviflora L. Iran J Basic Med Sci 2016; 19(5): 529-41.
17. Nasirpour M, Yavarmanesh M, Mohhamadi Sani A, Mohamdzade Moghadam M. Antibacterial effect of aqueous extract of Artemisia aucheri, Artemisia sieberi and Hyssopus officinalis L. on the food borne pathogenic bacteria. FSCT 2015; 12:73-84.
18. Soheili V, Khedmatgozar Oghaz N, Sabeti Z, Fazly Bazzaz BS. The novel effect of cis-2-decenoic acid on biofilm producing Psudomonas aeruginosa. Microbiol Res 2016; 6: 1. doi: .org/10.4081 /mr.2015.6158
19. Boyle VJ, Fancher ME, Ross RW. Rapid, modified Kirby-Bauer susceptibility test with single, high concentration antimicrobial disks. Antimicrob Agents Chemother 1973; 3: 418-24. doi: 10.1128/aac.3.3.418
20. Ashrafpour M, Rezaei H, Sefidgar A, Baradaran M, Sharifi H. Survey of the antibacterial properties of aqueous ethanolic and methanolic extraction of Artemisia annua around the city of Babol. J Ilam Uni Med Sci 2015;23: 129-41.
21. Gholampourazizi E, Rouhi S, Nouri B, Hassanzadeh Miandasteh SH. In vitro study of antifungal effect of walnut (Juglans regia L.) leaf extract on the Malassezia furfur fungus. SJKUMS 2015;20: 30-9. 22.
22. Ramezani M, Fazli-Bazzaz BS, Saghafi-Khadem F, Dabaghian A. Antimicrobial activity of four Artemisia species of Iran Fitoterapia. 2004; 75:201-3. doi: 10.1016/j.fitote.2003.11.006
23. Ashrafpour M, Rezaei H, sefidgar A, Baradaran M, Sharifi H. Survey of the Antibacterial Properties of Aqueous Ethanolic and Methanolic Extraction of Artemisia Annua Around the City of Babol. J Ilam Uni Med Sci 2015; 23:129-41.
24. Guan X, Ge D, Li S, Huang K, Liu J, Li F. Chemical composition and antimicrobial activities of Artemisia argyi Lévl. et Vant essential oils extracted by simultaneous distillation-extraction, subcritical extraction and hydrodistillation. Molecules 2019; 24:483.doi: 10.3390/ molecules 24030483
25. Rouhi S, Ramazanzadeh R, Mohammadi Sh, Abodollahi A, Hakib P, Mohammadi B, et al. Antibacterial effects of Artemisa aucheri leaf and Spirulina Blue-Green algae aqueous and alcoholic extracts on the multidrug-resistant Klebsiella pneumoniae isolated from the patients with pneumonia. SJKU 2020; 25:124-39.
26. Shojaei Baghini G, Akhavan Sepahi A, Rafiei Tabatabaei R, Tahvildari K. The combined effects of ethanolic extract of Artemisia aucheri and Artemisia oliveriana on biofilm genes expression of methicillin resistant Staphylococcus aureus. Iran J Med Microbiol 2018;10:417–23.
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Bagheri yazdi H, Norouzi taheri H. Antimicrobial Effects of Aqueous-Alcoholic Extract of Artemisia Turanica against Methicillin-Resistant Staphylococcus aureus (MRSA): An in vitro Study. J. Ilam Uni. Med. Sci. 2022; 30 (2) :1-7
URL: http://sjimu.medilam.ac.ir/article-1-7161-en.html
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Volume 30, Issue 2 (6-2022) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
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