[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
Publication Ethics::
Peer Review Process::
Indexing Databases::
For Authors::
For Reviewers::
Subscription::
Contact us::
Site Facilities::
::
Google Scholar Metrics

Citation Indices from GS

AllSince 2019
Citations62733583
h-index2719
i10-index18478

..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Registered in

AWT IMAGE

AWT IMAGE

..
:: Volume 26, Issue 3 (9-2018) ::
Journal of Ilam University of Medical Sciences 2018, 26(3): 38-46 Back to browse issues page
Comparison of the Effect of Garlic and Thyme Plants on Candida albicans: A Systematic Review and Meta-analysis
Shahin Mohammadi1 , Hossein Ebrahimi2 , Koroush Sayehmiri * 3
1- Student Research Committee, Faculty of Alleid Medical Sciences, Ilam University of Medical Sciences, Ilam, Iran
2- Department of Sport Physiology, Bakhtar University, Ilam, Iran
3- Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran , sayehmiri@razi.tums.ac.ir
Abstract:   (5042 Views)

Introduction: With the increased prevalence of candidiasis in recent years, the use of herbal medicines including garlic and thyme is considered to treat Candida albicans infection. We sought to compare the effectiveness of garlic and thyme on Candida albicans infection using a systematic review and meta-analysis.
 
Materials and Methods: IranMedex, PubMed, Google scholar, Magiran and  SID databases were searched and 12 experimental articles performed in Iran were retrieved. Data were extracted using  STATA software (version 12.2) and analyzed by meta-analysis and random effects model.
 
Findings: The overall sample size of the 12 articles was 276. In five papers, the effectiveness of garlic in the inhibition of Candida albicans was considered, and the values of minimum inhibition concentration (MIC) 90 and 50 were 0.062 and 0.0312 mg/ml, respectively. In seven papers, the inhibitory effect of thyme against Candida albicans was considered, and the MIC 90 and MIC50 values were 2. With the combination of P-value obtained by the Fisher’s exact test in the mentioned studies, we noted that garlic and thyme had significant inhibitory effects against Candida albicans (P<0.001).
 
Conclusion: Considering the low MIC50 and MIC90 of garlic compared to thyme, it can be stated that garlic is more effective in inhibiting Candida albicans than thyme. 

Keywords: Thyme, Garlic, Candida albicans, Fungus, Meta-analysis
Full-Text [PDF 547 kb]   (2215 Downloads)    
Type of Study: Applicable |
Received: 2016/11/10 | Accepted: 2017/04/23 | Published: 2018/09/15
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mohammadi S, Ebrahimi H, Sayehmiri K. Comparison of the Effect of Garlic and Thyme Plants on Candida albicans: A Systematic Review and Meta-analysis . J. Ilam Uni. Med. Sci. 2018; 26 (3) :38-46
URL: http://sjimu.medilam.ac.ir/article-1-3933-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 26, Issue 3 (9-2018) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
Persian site map - English site map - Created in 0.15 seconds with 40 queries by YEKTAWEB 4643