[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
Publication Ethics::
Peer Review Process::
Indexing Databases::
For Authors::
For Reviewers::
Subscription::
Contact us::
Site Facilities::
::
Google Scholar Metrics

Citation Indices from GS

AllSince 2019
Citations62433553
h-index2719
i10-index18377

..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Registered in

AWT IMAGE

AWT IMAGE

..
:: Volume 25, Issue 6 (3-2018) ::
Journal of Ilam University of Medical Sciences 2018, 25(6): 97-105 Back to browse issues page
Investigating Classes of Integrons in Salmonella infantis Isolated from Clinical Samples and their Antibiotic Resistance Profile
Fatemeh Abaspour Shoushtari1 , Kumarss Amini * 2
1- Dept of Microbiology, Saveh Branch, Islamic Azad University, Saveh, Iran
2- Dept of Microbiology, Saveh Branch, Islamic Azad University, Saveh, Iran , dr_kumarss_amini@yahoo.com
Abstract:   (13071 Views)

Introduction: Salmonella is one of the most important food-borne pathogens and zoonotic agents all over the world. Antibiotic resistance is a growing problem in Salmonella isolates and spreading of resistance genes by integrons to susceptible strains is one of the major concerns in the emergence of resistant strains. The aim of the current study was the identification of classes of integrons in the Salmonella infants isolated from clinical samples and their antibiotic resistance profile.
 
Material & Methods: In the cross-sectional study, 101 salmonella isolates were obtained from the stool samples. The antibiotic susceptibility test was determined using the disk diffusion method agreeing with CLSI guideline. Cellular DNA was extracted by AccuPrep Genomic DNA Extraction Kit and MPCR was performed for the identification of the intI, intII and intIII genes.
 
Findings: Sixty S. infantis isolates were collected using biochemical and microbiological tests. The lowest resistance rate in all isolates was related to Ceftriaxone (45%). The molecular analysis of classes of integrons showed 59 (98.3%), 51 (85%) and 23 (38.3%) isolates caring intI, intII and intIII genes, respectively.
 
Discussion & Conclusions: The result of this study showed that due to increased level of drug resistance in S. infantis and the presence of class 1 integron in these strains, resistance can be transferred to other food borne pathogens.

Keywords: Integrons, Salmonella infantis, Antibiotic resistance, Clinical samples
Full-Text [PDF 745 kb]   (1463 Downloads)    
Type of Study: Research |
Received: 2016/03/20 | Accepted: 2016/09/6 | Published: 2018/03/11
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Abaspour Shoushtari F, Amini K. Investigating Classes of Integrons in Salmonella infantis Isolated from Clinical Samples and their Antibiotic Resistance Profile . J. Ilam Uni. Med. Sci. 2018; 25 (6) :97-105
URL: http://sjimu.medilam.ac.ir/article-1-3456-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 25, Issue 6 (3-2018) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
Persian site map - English site map - Created in 0.15 seconds with 40 queries by YEKTAWEB 4643