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Pulmonary Function Test Results in Patients
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Abstract: (41886 Views) |
| Introduction: Pulmonary complication of IBD include airway inflammation involving small and large airways, pulmonary paranchymal disease, and serositis. The aim of this study was to determine the prevalence of Pulmonary Function Test (PFT) possible abnormality in ulcerative colitis (UC) patients.
Materials & Methods: In this cross sectional study, during spring and summer of 2006, PFT (spirometry & body box plethysmography) of 50 UC patients were compared to 50 healthy people of the same age and sex (control). Data collection forms including demographic specification and UC condition were filled. Out, and then analyzed by SPSS 10.
Findings: Mean age was 37.2(SD=14.57). Active UC was seen in 24.3% of patients. 24.9% of the patients had severe UC. PFT result demonstrated 100% air trapping(only increase in Residual Volume/Total Lung Capacity) 20% small airway obstructive pattern (only decrease in maximal expiratory flow at 25-75% of vital capacity) 12% restrictive ventilation defect 2% obstructive airway 2% hyperinflation and 6% upper airway obstructive pattern. There was a significant relationship between small airway obstructive pattern and duration of UC, (PV<0.05), and no relationship between other pulmonary disorders and severity, activity, duration of UC was observed.
Discussion & Conclusion: According to high prevalence of air trapping, small airway disease may be the prominent feature of lung involvement in UC patients. Therefore, a meticulous work-up for respiratory diseases seems necessary in UC patients. |
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| Keywords: pulmonary function test (PFT), ulcerative colitis (UC), IBD (Inflammatory Bowel disease) |
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Full-Text [PDF 2644 kb]
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Type of Study: Research |
Subject:
General
Received: 2011/07/25 | Published: 2011/04/15
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