[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
Publication Ethics::
Peer Review Process::
Indexing Databases::
For Authors::
For Reviewers::
Subscription::
Contact us::
Site Facilities::
::
Google Scholar Metrics

Citation Indices from GS

AllSince 2019
Citations63853687
h-index2720
i10-index18983

..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Registered in

AWT IMAGE

AWT IMAGE

..
:: Volume 24, Issue 2 (6-2016) ::
Journal of Ilam University of Medical Sciences 2016, 24(2): 38-46 Back to browse issues page
Effects of Feeding Flaxseed Oil (Linum usitatissimum) on Brain Edema and Blood Fat Levels in the Rat Stroke Model
Seyed vahid Hosseini1 , Mehdi Rahnema * 2
1- Islamic Azad University, Zanjan Branch
2- Islamic Azad University, Zanjan Branch , meh_rahnema@yahoo.com
Abstract:   (7465 Views)

Introduction: Cerebral ischemic edema is one of the most important complication of cerebral stroke that result in intensification of early (primitive) ischemic lesion in brain. In this study, we determinate relationship between effect of pre-nutrition of flax seed oil on level of blood oils and the amount of cerebral edema in model of rat stroke.

Materials & methods: This study was performed on 5 groups included 7 male rats. Blank group received distil water, where 3treatment groups received flax seed oil by gavage 30 days. (0.25,0.50,0.75). For sham  group isn't performed treatment and  ischemic induction. Two hours after the last gavege, group operated by surgery of model MCAO(Middle Cerebral Artery Occlusion) for ischemic induction and study of cerebral ischemic and blood oils. Data were analyzed by test ANOVA investigation.

Findings: Pretreatment with flax seed oil resulted in decrease of cholesterol, triglycerides and LDL and also resulted in increase of level of HDL in doses of 0.50 and 0.75(P<0.05) Pretreatment by flax seed oil resulted in decrease of the amount of cerebral edema after MCAO in rat (P<0.05).

Discussion & Conclusion: Results of this study indicated that flax seed oil with doses of 0.50 and 0.75 protected ischemic rat in contrast to cerebral edema and decreased the amount of serum lipids.

Keywords: Cholesterol, Triglycerides, Flaxseed oil, Ischemic, Cerebral edema
Full-Text [PDF 629 kb]   (3414 Downloads)    
Type of Study: Research | Subject: physiology
Received: 2015/06/10 | Accepted: 2015/08/31 | Published: 2016/06/13
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hosseini S V, Rahnema M. Effects of Feeding Flaxseed Oil (Linum usitatissimum) on Brain Edema and Blood Fat Levels in the Rat Stroke Model. J. Ilam Uni. Med. Sci. 2016; 24 (2) :38-46
URL: http://sjimu.medilam.ac.ir/article-1-2778-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 24, Issue 2 (6-2016) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
Persian site map - English site map - Created in 0.15 seconds with 41 queries by YEKTAWEB 4646