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Effects of Drug Combined of Black And White Alum on Cutaneous Leishmaniasis Lesion
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افرا خسروی *   1 |
| 1- , am_bahram2002@yahoo.com |
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Abstract: (22255 Views) |
| Introduction: Leishmaniosis is a parasitic disease of man and animal with different clinical performance. WHO has suggested the disease to be investigated and supported from different points of view. The treatment of leishmaniosis is still based on using different compounds of antimonite drugs which cause variety of side-ffects. Furthermore, resistance of parasites to this type of drug is an increasing problem. This is one reason along with being an epidemic disease in Ilam for our research to be accomplished. Materials & Methods: In this study, 36 patients with their own written agreements, were divided into 3 groups, each group included 12 cases. The fist group was studied as the control part-taker receiving treatment with amphotericin B, the 2nd group were treated with local formulated drug (no 1), and the 3rd group received treatment with local made drug of more concentration (no2) under consultation of a physician. To conform the presence of amastigotes in patients, we used three different methods as follows: biopsy, culture media (NNN) and Smear. Findings: Both the local made formulated drugs with two different concentration compounds showed different positive effects on leishmaniosis wounds However, the 2nd local made drug showed better results in comparison with that of amphotricin B. Regarding the drug complications, in comparison with amphotricin B, the itching around wounds in patients who had used local made formulated drugs did not experience stresses and feelings of itching, but those patients who had used chemical drug had suffered lot of itching in the area as well as a lot of stresses during treatment. Regarding the control of the wound diameter in the patients, the local made drug proved more effective than amphotricin B. Discussion & Concusion: In compound made local drug of black and white alum, sulphate of cooper %1 and butter, there is an effective factor for controlling cutanouse leishmaniosis |
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| Keywords: leishmaniosis, lesion, alum, sulphate of cooper |
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Full-Text [PDF 776 kb]
(2785 Downloads)
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Type of Study: Applicable |
Subject:
General
Received: 2010/06/2 | Accepted: 2015/04/20 | Published: 2015/04/20
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