Introduction: Postoperative nausea and vomiting (PONV) is the most frequent side effect after anesthesia, occurring in 20-70% of patients during the first 24 h after surgery. Some studies indicate that an increase in inspired oxygen concentration can decrease incidence of PONV. In this study, we tried to evaluate the effects of supplemental 100% oxygen on PONV in patients undergoing breast surgery.
Materials & Methods: In a clinical double-blind study, 60 patients receiving standardized halothane anesthesia were randomly assigned to the following two groups: group 30 (30% oxygen in air) and group 100 (100% oxygen). Postoperative nausea and vomiting were assessed over the first 24 h after surgery in both the groups.
Findings: There was a significant difference between the two groups.( PONV was 30% in group 100 versus 64% in group 30).(p value <0.05)
Discussion & Conclusion: This study showed that intraoperative high oxygen concentration effectively prevents PONV after breast surgery and reduces the need for antiemetic drugs in these groups of patients.
گلفام ف. Effects of Supplemental Oxygen for Prevention of Nausea And Vomiting After Breast Surgery. J. Ilam Uni. Med. Sci. 2010; 17 (4) :31-35 URL: http://sjimu.medilam.ac.ir/article-1-163-en.html