Tumor markers are soluble substances in body fluids such as blood, urine, serum and tissues that are increased in patients with cancer. Most of the tumor markers are proteins that are increased in response to changing in the condition of cancer or are directly secreted by the cancer cells. Furthermore, most of the tumor markers are also made by normal cells and their amount is low in the cells: however the expression of tumor markers is increased or decreased in tumor cells thereby their amounts are elevated in blood and body fluids. This article sought to review the recentl-y published data on the diagnosis of cancer cells with the aid of tumor markers through proteomics approaches.
Chavoshi S, haidari kashl S, rezaee tavirani M, ebrahimi M, etedali A, Raessodati R, et al . Tumor Markers at a Glance. J. Ilam Uni. Med. Sci. 2013; 21 (6) :143-159 URL: http://sjimu.medilam.ac.ir/article-1-1480-en.html