Purpose: The studies has been shown that insufficient recovery between sessions cause immune suppression. The aim of this study was to investigate the effect of repeated bouts resistance and endurance exercise on blood leukocytes, lymphocytes, neutrophils, monocytes count and plasma cortisol levels in athlete girls. Materials and Methods:19 athlete girls (ages, 20- 25 yr), volunteers participated in the study, in two phase and two separate days performed two experimental protocols. At first, subject performed two bouts of resistance exercise (8 exercise with 65% 1RM) at 09:00 and 15:00. After one week rest, subject performed two bouts of endurance exercise (60 min cycling on 65% HR Reserve) at same time. Blood samples were taken before and after each bout and 1 hour after second bout of exercise. Statistical analysis was performed using a Kolmogroph-Smirnoff, independent t-test and ANOVA with repeated measure. Results: Repeated bouts endurance exercise significantly increased blood leukocytes, neutrophils, monocytes count and plasma cortisol levels, but of repeated bouts resistance exercise only significantly increased blood lymphocytes count (P˂0.05). Comparison of two type exercise indicate only significantly difference in blood monocytes count (P˂0.05). Conclusion: This results has been shown that no significantly difference between repeated bouts of resistance and endurance exercise in a day, on immunological variables and cortisol hormone.