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  Introduction: Gestational diabetes, the most common metabolic disorder in pregnancy, causes serious complications in mothers and their fetus . So, knowing the risk factors of gestational diabetes is very important, because through understanding these risk factors it helps to establish screening programs for susceptible mothers and also early diagnosis of disorders. Furthermore, efficient control of blood sugar protects mothers against complications and consequently their fetus. The goal of our study was to evaluate the correlation between gestational diabetes and polycystic ovary syndrome.

 

  Materials &Methods: This study was a case - control research. Pregnant women admitted at Akbar Abady hospital of Tehran were studied during 1998-2005. 188 women participated in this study of whom 94 mothers were put into the case group (with gestational diabetes) and the other 94 mothers were in the control group (without gestational diabetes). Then history polycystic ovary syndrome was investigated between the two groups. The data were analyzed using SPSS software, descriptive statistical, t- test, fisher, x2, Mann- Whitney and Odds ratio.

 

  Findings: The results of this study showed no dissimilarities between the two groups regarding the mean of age, educational level, apgar score and gravida. But there was significant difference in history olligomenorrea, kind of delivery, mean of the new-born weight and gestational age and body mass index in the two groups. Also, the results showed significant relations between those with gestational diabetes and women without gestational diabetes with the history of polycystic ovary syndrome. (p=0/03)

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  Discussion & Conclusion: Considering the results of our study indicating significant relations between diabetes and history of polycystic ovary syndrome, it seems necessary to establish screening programs in women with history of polycystic ovary syndrome, while early diagnosis of gestational diabetes protects mothers and their fetus against any complications.

 

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Bacgrond and Aim: Oral health is an important component of lifestyle. And recovery requires proper training methods to improve knowledge, attitudes and practices in relation to its population. The aim of this study was to compare the effect of lecture and video screening in improving the knowledge, attitude and practice of dental hygiene students. Methods:The survey is a quasi-experimental intervention survey done in Chabahar in 2011-2012. By sampling a regular allocation process is divided into three equal groups (each group n = 100:control, lecture and film) were divided..Knowledge, attitude and Practice student were measures by self report questionnaires and pre-test and post-test . And relevant data was analysed by using of software SPSS VERZHON 11, statistical tests ANOVA, Mann-Whitney. Results :The Lecture And Film Group knowledge And attitude immediatelly and 3 months after the intervention, the practice immediately after the intervention increased But A more effective approach to video on improving the knowledge, attitude and practice of oral health revealed (P <0/001). Conclusion:This study showed that both the training lectures and video display can be an effective way to promote Oral health Education Knowledge , attitudes and practice of the people Although video method is more effective.

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Introduction: Cancers are one of the main causes of death in human societies. No-wadays, cancer screening tests are used for early detection and on time treatment in the early stages of disease. It is important to improve the consequences, survival rate, and saving patient´s life. This study was done to investigate the preventive and impeller factors of common cancers by screening tests for women in Kashan city. Materials & Methods: This descriptive study was conducted on 851 married wo-men (15-70 years old) in Kashan. Samples were selected by simple sampling method among married women referred to health centers of Kashan. For data collection, a questionnaire consisting of three parts was used: Demographic information, breast self-examination, mammography and Pap smear and study of preventive and impeller factors in screening tests. Descriptive and analy-tical information was analyzed by Chi-sq-uare test in SPSS Findings: The results showed that 75.2% of the subjects were 40 years old. The main impeller factors to do Pap smear screening included: Seriousness of cancer (%64.9), advice of health personnel (%57.9), and accessibility to health care centers (%55.1). In this respect, breast self-examination received a percentage of 58.2, 47, and %41.2, respectively, and mammograp-hy had a percentage of 15, 9, and %9, respectively. The most important preventive factors for screening tests (all of three mentioned tests) were included absence of problems, unawareness of cancer risk, and the fear of inflicting with cancer. Discussion & Conclusion: According to the results, women's awareness about the importance of early detection of breast and uterine diseases leads to their participation in the screening programs.

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Introduction: In the current study, to reduce the side effects of anti-inflammatory drugs and increase their specificity, a new pharmaceutical inhibitor was designed by computational Biology and Bioinformatics knowledge.

Materials & methods: For this purpose, first, 150000 compounds with medicinal properties from ZINC database and also the files related to the structure of the enzyme cyclooxygenase2 from RCSB (Research Collaboratory for Structural Bioinformatics) were extracted. After preparing them, all of these chemical compounds were docked with the target enzyme in order to select the best pharmaceutical inhibitor (ligand).

Findings: After checking the computation, 10 compounds of ligands that were the results of Docking, were selected according to the Gibbs free energy (least ΔG). Based on the results of the docking operation, inhibitor binding to cox2 causes conformational changes of enzyme, potential energy reduction, and increasing the stability of inhibitor-enzyme complex.

Discussion & conclusions: According to the results obtained from the study, the inhibitors can reduce the inflammation and pain in different inflammatory diseases, by placing in the active site on the basis of more specificity and finally less toxicity.

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Introduction: Cervical cancer is the fourth most common cancer in women worldwide that causes more mortality each year. Given that lack of regular screening for cervical cancer is associated with an increased risk of 2 to 6 times and that the Health Belief Model (HBM) has been introduced as a suitable model to improve screening behaviors, this study was conducted aimed to survey the effect of blended educational program on cervical cancer screening behavior based on HBM among housekeeper women.

Materials & methods: In this quasi-experimental study, 120 individuals of housekeeper women referring to health centre in West Eslamabad city were randomly selected. Using standardized questionnaire knowledge, HBM items and Pap test performance were measured before and after 3 months of educational intervention. The educational intervention consisted of four sessions of 45-minute-long of four weeks. Data were analyzed by software spss 21 and descriptive statistics (frequency, mean and standard deviation) and analytical (paired t, independent t and Chi-square tests) at the significant level of less than 0.05.

Findings: After the educational intervention, the mean scores of knowledge and HBM items except the perceived severity, were significantly higher in the intervention group compared to control group (p<0.05). Also, after intervention, 66.7 percent of women in the intervention group the ability of Pap smear screening compared to the controls were obtained.

Discussion & conclusions: The results of current study showed that the combined program consisting of BEP and HBM provide a suitable framework for developing educational interventions regarding Pap test practice.

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