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Showing 3 results for Herbal
S Fayaz Far, M Zamanyan Azodi, Saeyd Heydari Kashel, Faryd Azizye Jalileyan,
Volume 20, Issue 5 (3-2013)
Abstract
Abstract
Background and aim: Colon cancer is the second lethal cancer after lung cancer. Due to the existence of many side effects and problems in the ways of cancer treatment arising from surgery, chemotherapy or radiotherapy at the present, the need for such ways to be replaced and new drugs is prominent. Usage of herbal essential oils as drug contributes to a major part of traditional and Islamic medicine. This project aims at studying of anticancer activity of Cuminum cyminum essential oils on human colon cancer cell line (SW742).
Materials and Methods: Essential oils are provided by distillation method and their cytotoxicity effects on SW742 cell line were investigated. Human fibroblast cell was used as healthy and control cells. The cells were cultured and different concentrations of each essential oil were induced to cells. After 48 h incubation, cell survival with MTT assay was studied via the statistical methods (software SPSS), averages and standard deviations were achieved and diagrams were drawn.
Results: Findings indicate that essential oil affects on cell survival by two different ways evaporation part reduces the cell growth enormously of both cancer and fibroblast cells. Soluble part, on the other hand, stimulates cell growth of fibroblast cells, while reduces cell growth of cancer cells.
Conclusion: Analytical data provide considerable information about pharmaceutical properties of this plant. Even though, more evaluations are needed to investigate the exact effects of this plant.
M Nazari, I Pakzad, A Maleki, A Hematian,
Volume 22, Issue 3 (7-2014)
Abstract
Introduction: The most important nosocomial infectious agents are Staphylococcus aureus (S. aureus), Pseudomonas aeruginosa (P. aerug-inosa), and Helicobacter pylori (H. pylori). An alternative way for treatment of bacterial infection is herbal therapy. The aim of this study was to evaluate the inhibitory effects of alcoholic and water extracts of Scrophularia striata (S. striata) plant on S. aureus, P.aer-uginosa and H. Pylori at in vitro condition.
Materials & Methods: Water and alcoholic extracts of S. striata plant were prepared. Inhi-bitiory effect of these extracts was examined on S. aureus and P.aeruginosa in Mueller-Hi-nton agar medium. MIC and MBC of the ext-racts was determined in TSB medium by ma-cro dilution method. MIC and MBC of H. Pylori was determined by agar diffusion me-hod.
Findings: Inhibitory zone of water extraction for S. aureus and P. aeruginosa was 16 mm and 24 mm, respectively. Inhibitory zone of etha-nol extract for S. aureus and P. aeruginosa w-as 11 mm and 12 mm and that of methanol ext-ract was 12 mm and 16 mm, respectively.
The chloroform extract had not any inhibitory effect. The MIC of water extract of S. striata for S. aureus, P. aeruginosa and H. Pylori were 15µg/ml, 20µg/ml, and 5µg/ml, respectively. Also, the figures of MBC were 10µg/ml, 40µ-g/ml and 50µg/ml, respectively.
Discussion & Conclusion: Water and methanol extracts of S. striata had better inhibitory effect then other extracts. The best effect was belo-nged to the 5-hour boiled extract of the plant. Given to the MIC and MBC values, water extr-act of S. striata may be a candidate for herbal therapy in bacterial infections
N Samadi, F Amani, M Naghizadeh, I Alahiari, S Ghezelbash, R Kazemzadeh,
Volume 22, Issue 6 (1-2015)
Abstract
Introduction: Medicinal herbs have a history as old as human creation and using them as a healing agent has been common all over the world since anci-ent times. Medicinal herbs have been also used in treating dysmenorrheal as one of the most common gynecological problems in women. In recent years, a variety of nutrition therapies have been used for the treatment of dysmen-orrheal. But considering that the use of any medication has side effects in addition to therapeutic effects, using chemical plants along the drug may be helpful in the treatment of dysme-norrheal. Therefore, this study aimed to determine the effect of medicinal herbs in relieving the symptoms of dysmenorrheal among female students in Ardabil University of medical scie-nces.
Materials & Methods: This is a quasi-experimental study which was done on 90 female students in Ardabil Univ-ersity. Random sampling was done during 6
month in 2013, and the data collection instruments included demographic ch-aracteristics and visual pain scale. D-escriptive and inferential statistics were used for the data analysis.
Findings: The results of this study sho-w that there was a statistically signify-cant relationship between symptoms of pain before and after taking a com-bination of herbs (P=0.017).
Discussion & conclusion: The results of the study showthat the use of herbs (combination of fennel, chamomile and ginger) is effective in relieving the sy-mptoms of dysmenorrheal. Consid-ering the high prevalence of primary dysmenorrheal and Iran’s potential in the field of herbal medicine, herbal re-medies are recommended in dysmen-orrheal pain relief along with other treatments.
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