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Showing 5 results for Adiponectin
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Volume 18, Issue 4 (1-2011)
Abstract
Introduction: Preeclampsia, a pregnancy specific syndrome, is a major cause of maternal and perinatal morbidity and mortality. The aim of the present study was to assess relationship between leptin and adiponectin, and leptin/adiponectin ratio in preeclamptic women compared with normal pregnant women. Materials & Methods: A cross-sectional study was designed. The patients consisted of 30 preeclamptic women. The control group consisted of 30 healthy pregnant women. Serum levels of total leptin and adiponectin were assessed using commercially available enzyme-linked immunosorbent assay (ELISA) methods. The unpaired Student’s t-test and Pearson’s correlation analysis were used for statistical analysis. Findings: Serum levels of leptin were significantly higher in preeclamptic group than in normal control group, while adiponectin levels decreased. There was a significant negative correlation between leptin and adiponectin in normal control group and also in preeclamptic women. The leptin/adiponectin ratio increased significantly in preeclamptic patients. Discussion & Conclusion: The findings of the present study suggest that increase in leptin and decrease in adiponectin levels can help as a biomarker for diagnosis of severe preeclampsia.
A Abdolmaleki, M Samavati Sharif, P Nikbakht Nasrabadi, R Amini,
Volume 22, Issue 5 (10-2014)
Abstract
Introduction: Recently, investigating the effect of different training methods, especially high-intensity interval training, on risk factors of obesity has been dramatically expanded. Hence, the aim of
this study was to investigate the effects of 12 weeks of low-volume high-intensity interval training and traditional continuous exercise training on adiponectin levels and lipids profile in obese young men.
Material & Methods: The subjects of this study were 34 obese young men (age: 22.4±3.6 years, BMI: 32.98±2.4 kg/m2) that were randomly divided into three groups of low-volume high-intensity interval training (LVHIIT) (n=11), traditional continuous exercise training (TCET) (n=11) and control (n=12). Experimental groups trained 12-weeks and 3 times in a week. Control group subjects performed only their routine activities. For data analysis, one way ANOVA and paired t-test were used.
Findings: The results showed that lipids profile and adiponctin resting levels im-proved significantly in experimental groups compared with pre-test values (p<0.05). Resting levels of adiponectin in
LVHIIT group was significantly higher than in control group (p=0.037), but no differences were found between the experimental groups (p>0.05).
Discussion &Conclusion: According to the profound differences in training volume of experimental groups, it is appeared that LVHIIT is comparable with TCET in terms of duration, and also reduces some of the risk factors of obesity.
Sara Gharibshi, Vahid Tadibi, Sakineh Nikseresht, Naser Behpoor, Dariush Sheikholeslami Vatani, Ehsan Hoseinibidokhti,
Volume 23, Issue 3 (9-2015)
Abstract
Introduction: Adiponectin is a hormone that plays an important role in diet-induced insulin resistance. People with higher weight have a lower adiponectin levels and are more susceptible to type II diabetes. Studies have shown that exposure to altitude and hypoxic environment causes weight loss. The aim of this study was to investigate the effect of intermittent hypoxia on adiponectin level and BMI in obese people with type II diabetes.
Materials and methods: Ten obese subjects with type II diabetes participate in the study with mean BMI of 32.02 ± 2.47 and age range of 50-70 years old. The intervention consisted of 14 sessions of intermittent hypoxia, one hour per day for 14 consecutive days. Plasma adiponectin and BMI were measured three times (pretest, day 7, and posttest) and two times (pre- and post-tests).
Findings: Plasma adiponectin showed a non-significant 2.1% reduction, 6 days after intermittent hypoxia intervention (day 7) (t9= 1.06 p=0.317). Also, in fifteenth day or after 14 days of intermittent hypoxia intervention, plasma adiponectin levels had a 5% non-significant reduction compared to the pretest (t9= 0.578 p=0.577). The results of present study also showed that short-term (7 days) and medium term (14 days) exposure to intermittent hypoxia had no effect on BMI (p> 0.05).
Discussion & Conclusion: Findings of present study indicate that performing 6 and 14 one-hour sessions of intermittent hypoxia in consecutive days cause no significant effect in plasma adiponectin and BMI of obese people with type II diabetes.
, , ,
Volume 24, Issue 1 (4-2016)
Abstract
Introduction: Obesity is the consequence of an excess of adipose tissue, resulting from an imbalance between food intake and energy expenditure. Exercise training due to increase energy expenditure, can play an affective role in decrease adipose tissue. The aim of the present study was to investigate the effect of the High Intensity Interval Training (HIIT) on adipose tissue levels of adiponectin and plasma insulin and glucose in male rats.
Materials & methods: 20 male rats (8 week years old) were randomly divided in to two training and control groups and each group consists of 10 rats. Training program performed in 5 weeks, and 5 sessions per week. Male wistar rats completed 6 HIIT bouts with 2 minutes duration and 37 m/min in first week, between each bout, rats resting for one minute. In second, third and fourth weeks, number of bouts increased respectively to 7, 9 and 10. In the final week (fifth week), 12 HIIT bouts with 52 m/min speed performed. To measure study variables, 72 hours after last exercise training session, blood samples were collected and visceral and subcutaneous adipose tissue removed. Independent t-test was used to analyze the data.
Findings: Significant increase in levels of visceral adipose tissue Adiponectin (p<0/001) and significant decrease of plasma insulin (p<0/001) were observed in training group. But variation in levels of Adiponectin in subcutaneous adipose tissue and plasma glucose were not significant (p>0/05).
Discussion & Conclusions: The results of present study indicated that HIIT can result in increase in subcutaneous and visceral adipose tissue levels of adiponectin. In the present study improvement in insulin sensitivity are related to increase levels of adiponectin in adipose tissue and HIIT as effective factor induce decrease adipose tissue as well.
Mohammad Parastesh, Abbas Saremi,
Volume 27, Issue 1 (4-2019)
Abstract
Introduction: Changes in plasma adipicin and inflammatory parameters in type 2 diabetes are due to obesity and directly related to the condition of diabetes. The aim of this study was to investigate the effect of High intensity interval training (HIIT) on the ratio of adiponectin to leptin and C-reactive protein (CRP) in type 2 diabetic rats.
Materials & Methods: In this experimental study, 42 Wistar rats with mean weight of 205±54 were randomly assigned to healthy control, diabetic control and diabetic training groups. The diabetic training group received ten weeks of HIIT training following the induction of diabetes. At the end of the experimental period, blood samples were taken to assess leptin, adiponectin and insulin resistance. Data were analyzed by one-way ANOVA and Tukey's post hoc test at a significant level of 0.05%.
Findings: The induction of diabetes by streptozotocin-nicotinamide resulted in a significant decrease in adiponectin (P =0.000) and leptin (P=0.000) and a significant increase in C-reactive protein (P=0.000) in diabetic control group compared to healthy control group Became 10 weeks of HIIT training resulted in a significant decrease in fasting blood glucose (P=0.109), C-reactive protein (P=0.024), and a significant increase in serum leptin levels (P=0.001), adiponectin (P=0.42) In the HIIT training group compared to the diabetic control group.
Discussion & Conclusions: It seems that HIIT training improves inflammation (C-reactive protein) in type 2 diabetic rats by altering serum levels of adiponectin and leptin. In the present study, 10 weeks of HIIT training led to an increase in the ratio of adiponectin to leptin and consequent reduction of C-reactive protein.
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