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Showing 2 results for khalighi
Tayebeh Heydarizadi, Ebrahim Khalighi, Korosh Sayehmiri,
Volume 23, Issue 1 (4-2015)
Abstract
Introduction: Spinal anesthesia compared to general anesthesia is a safer method. Reduced headaches and back pain after spinal anesthesia, may cause more Selection of these method. In this study, the relationship between weight gain during pregnancy with headache and back pain after spinal anesthesia in patients undergoing cesarean section is checked.
Materials & Methods: This study was performed on 100 patients for elective cesarean section. age, height, weight before pregnancy and during the cesarean section was recorded. Headache and back pain patients classified according to the score of VAS (Visual Analog Scale) that 0-10 are defined in the immediate postoperative recovery and discharge 1, 2, 6,12,24,48 hours after surgery was measured. Findings: Pearson correlation coefficients showed that there was a direct correlation between the weight gain during pregnancy and headache after spinal anesthesia in patients (p=0.047،r=0.20). Weight gain causes back pain decreased in patients, but the decrease was not statistically significant. (p=0.25 ،r=-0.11). In these cases there was no significant relationship between headache and back pain (p=0.68،r=0.45), between age of patient and severity of headache (p=0.025،r=0.80), height of patient and severity of headache (p=0.03،r=0.71), patient age and back pain (p=0.03،r=0.76), and the patient's height and back pain (p=0.05،r=0.55).
Discussion & Conclusion: Weight gain has an effect on the severity of the headache, but no effect on back pain intensity.
Fakhri Khalighi Sigaroudi, Mohammad Rostampour, Bahram Soltani Tehrani,
Volume 30, Issue 5 (12-2022)
Abstract
Introduction: Regarding the chronic nature of epilepsy and resistance to chemical drugs, herbal medicine has received remarkable interest. This study investiagted the anticonvulsant effects of hydro-alcoholic extract of Salix Alba leaves on PTZ-induced seizure in male mice.
Material & Methods: In total, 56 albino male mice weighing 20-25 g were divided randomly into seven groups (8 animals per group) including negative (saline), positive (Phenobarbital) control, and five groups which received different doses of hydro-alcoholic extract of Salix Alba leaves. After 45 min, all groups received the convulsant pentylene tetrazole, and the onset time of myoclonic, tonic-clonic seizures, and the 24-hour mortality rate were measured.
(Ethic code: IR.GUMS.REC.1394.566)
Findings: The extract significantly delayed the onset of myoclonic and tonic-clonic seizures at a dose of 100 mg/kg (P<0.01) and for other doses (P<0.001), compared to the control group. Moreover, the extract decreased the 24-h death. This was significant at 1000 mg/kg (P<0.001), as well as 300, 500, and 800 mg/kg (P<0.05), compared to the control group.
Discussion & Conclusion: It seems that the hydro-alcoholic extract of Salix Alba leaves has a significant diminishing effect on PTZ-induced seizures in male mice which is due to its anti-inflammatory and anti-oxidant effects.
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