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Introduction: Transportation of patients from operating room to recovery can cause hymodynamic changes. Factors that can affect hemodynamic and O2sat include: type of anesthetic, duration of surgery, transportation, age, previous underlying disease, …. There are poorly documented studies about such changes in children. So, the goal of this study was to evaluate the hemodynamic and O2sat variabilities among children at recovery room. Materials & Methods: In this prospective-discriptive study, 120 children aged 1-12 years undergoing minor surgery with general anesthesia were investigated. Systolic, diastolic and mean arterial pressure and O2sat were measured before the anesthesia and surgery, immediately before transfer to recovery and after arrival at recovery room. Data was analyzed by SPSS software. Findings: Mean systolic, diastolic, mean arterial blood pressure and O2sat in recovery room decreased and pulse rate increased significantly compared with the other times, (P<0.05). Discussion & Conclusion: Hypotension can be due to hypoxemia, decreasing in venous return and cardiac output. Tachycardia may be the result of compensatory response to hypotension, pain, hypoxia, and the stress due to extubation. Hypoxia may indicate upper airway obstruction, atelectasia and anesthetic depression. It can be suggested that careful and rapid transfer of children and O2 supplement during transfering to recovery room can prevent instability of the above parmeters.

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Introduction: In the present study, the ability of P19 embryonic carcinoma cell differentiation to cardiomyocytes in different concentrations of DMSO was evaluated.
Materials & Methods: In order to providing differentiated P19 cells, embryonic-like objects (Embryoid Bodies, EBs) formed during 2 days through hanging drops method. Then EBs induced for 18 days under the different concentrations of DMSO (0.1%, 0.5%, 1%, 1.5% and 2%). The rate of cardiomyocytes beating was counted with three days interval in the various groups by inverse microscope. Immunocytochemistry was used to illustrate expression of F-actin protein.
 Findings: Many morphological changes occurred in cardiomyocytes derived from P19 especially in DMSO 0.5% group, so a remarkable increase in the size of the cytoplasm and cytoplasmic processes was observed. The results revealed that the maximum beating frequency per minute was observed in DMSO 0.5% group concentration in 2+12 days (2 days for making emberyonic bodies, and 12 days after differentiation induction). In addition, only cardiomyocytes induced differentiation by DMSO 0.5% concentration expressed F-actin which was not expressed in the other concentrations.
 Discussion & Conclusion: The findings of this study suggest that, firstly, the most effective concentration in the process of cardiogenesis induction is 0.5%. Secondly, P19 carcinoma cells are desirable and susceptible to differentiate cardiomyocytes.

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Introduction: In addition to Helicobacter pylori, non-Helicobacter pylori helicobacters (NHPHs) have been diagnosed in the humans stomach that caused gastrointestinal diseases. This study aimed to evaluate the coinfection of H. pylori with NHPHs species in patients with gastric disorders in Iran.
 
Materials & Methods: This cross-sectional study was performed on 421 gastric biopsies form dyspeptic patients, who did not receive any treatment for H. pylori. The samples were divided into H. pylori-infected and NHPHs-infected groups, based on the rapid urease test, histological analysis of biopsies, and genotyping. After DNA extraction, genotyping of samples was performed to detect H. pylori and NHPHs with PCR of encoding genes fragments for urease A (ure A), urease B (ure B) and urease AB (ure AB).
 
Findings: The results of the present study revealed that  57 patients (19%) had coinfection H. pylori with one of the NHPHs,10 patients (3.3%) has coinfection of H. pylori with NHPHs for H. suis,22 patients (7.3%) had coinfection of H. pylori with NHPHs H. salomonis,17 patients(5.7%) had coinfection of H. pylori with NHPHs for H. heilmannii (5.7%) ,and  8 patients (2.7%) had Coinfection of H. pylori with NHPHs for H. felis.
 
Discussion& Conclusions: Based on the results of the current study, it can be conclude that difficulties and failures in the treatment of H.pylori is probably due to the coinfection of H.pylori with NHPHs species ;however,  this conclusion requires further investigations.Additionally,in coinfection H. pylori with NHPHs, H. salomonis was found to be the most prevalent in Iranian patients with gastric disorders.
 

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Introduction: Rheumatoid arthritis (RA) or arthritis is the most common systemic inflammatory disease of the joints and one of the chronic autoimmune diseases. The global prevalence of rheumatoid arthritis has been reported at 1%. Sodium benzoate (NaB) is a cinnamon metabolite used as a food preservative. This study aimed to evaluate the changes of CD₅₂ in the animal model of rheumatoid arthritis treated with NaB. Moreover, it was attempted to investigate the relationship between serum CD₅₂ and RA severity.
 
Materials & Methods: The male rats were divided into four groups of healthy, RA, RA treated with NaB, and RA treated with prednisolone. The RA was induced by intradermal injection of heat-killed Mycobacterium tuberculosis suspended in the Freund's incomplete adjuvant. During two weeks, from the 10th to 23rd days after RA induction, the disease progression was assessed through macroscopic examinations, including walking ability, redness of the skin, as well as swelling at the ankle, wrist, and small joints of the fingers. Clinical, radiological, and histological symptoms, as well as the serum protein levels of CD₅₂, were also investigated in this study. Ethics code: IR.sums.med.rec.1398.353
 
Findings: According to the results, the overall activity and walking ability of the RA rats decreased, compared to the healthy control group. Moreover, the severity of RA clinical symptoms was significantly reduced in the group treated with NaB and prednisolone, compared to the control group. There were no significant differences among the groups regarding the serum levels of CD_52..
 
 
Discussion & Conclusions: There were no significant differences among the groups regarding the serum change of CD₅₂ expression level indicating that the mechanism of the effect of NaB was not induced by CD₅₂.