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Introduction: The results of studies on the biological effects of ionizing radiation can play an important role in reducing the risk of occupational hazards of personnel working at the radiological departments of the hospital. This study aimed to investigate the concentration of aluminum, manganese, and selenium in the blood serum of operating room staff and their association with occupational radiation exposure.
 
Materials & Methods: In total, 100 healthy operating room staff was selected using systematic random sampling. They were then divided into three groups of radiation workers, non-radiation worker, and test (those who were exposed to X-rays but did not wear film badges). Subsequently, two milliliters of peripheral blood were taken intravenously from volunteers and centrifuged to separate serum. The concentration of three elements was read by the graphite furnace atomic absorption spectroscopy. The analysis of variance was used to analyze the concentration of aluminum, manganese, and selenium in all groups. Moreover, the fitting curve of the occupational exposure was described using the R software. Ethics code: ir.kums.rec.1397.467
  
Findings: The normality of the data was assessed and confirmed by the Kolmogorov-Smirnov test. Moreover, the concentration values (ng/ml) of aluminum, manganese, and selenium were 8.62, 9.08, and 76.15, as well as 13.53, 12.14, and 140.97 in the non- and radiation worker groups, respectively. The difference between the two groups was significant for all three elements (P<0.001). Furthermore, the corresponding values for aluminum, manganese, and selenium were 9.54, 8.76, and 105 in the test group.
 
Discussions & Conclusions: Occupational radiation can increase the concentration of manganese, aluminum, and selenium in the blood serum. These results suggest the necessity for more investigations on operating room personnel who do not wear film-badges.

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Introduction: Regarding the chronic nature of epilepsy and resistance to chemical drugs, herbal medicine has received remarkable interest. This study investiagted the anticonvulsant effects of hydro-alcoholic extract of Salix Alba leaves on PTZ-induced seizure in male mice.
Material & Methods: In total, 56 albino male mice weighing 20-25 g were divided randomly into seven groups (8 animals per group) including negative (saline), positive (Phenobarbital) control, and five groups which received different doses of hydro-alcoholic extract of Salix Alba leaves. After 45 min, all groups received the convulsant pentylene tetrazole, and the onset time of myoclonic, tonic-clonic seizures, and the 24-hour mortality rate were measured.
(Ethic code: IR.GUMS.REC.1394.566)
Findings: The extract significantly delayed the onset of myoclonic and tonic-clonic seizures at a dose of 100 mg/kg (P<0.01) and for other doses (P<0.001), compared to the control group. Moreover, the extract decreased the 24-h death. This was significant at 1000 mg/kg (P<0.001), as well as 300, 500, and 800 mg/kg (P<0.05), compared to the control group.
Discussion & Conclusion: It seems that the hydro-alcoholic extract of Salix Alba leaves has a significant diminishing effect on PTZ-induced seizures in male mice which is due to its anti-inflammatory and anti-oxidant effects.