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Abstract Introduction: HIV-Aids and hepatitis, B are the global problems that their destructive effects reduced life expectancies in millions of people. Although in some developed countries a significant success in control of these diseases had seen, but in developing countries still the expanding epidemic continues. One of the causes of prevalence and incidence of these two diseases is lack of the necessary knowledge in society, especially in those who are directly at risk of these diseases. This study aimed to assess Marvdasht barbers awareness in the field of transmission and prevention of Aids and hepatitis B. Materials and methods: this survey is a cross- sectional study.The study population include 180 Marvdasht barbers (110 males & 70 females). Data collection tools consisted of two parts: questions on demographic characteristics and questions related to knowledge about Aids and hepatitis B. SPSS soft- ware were used to analyzed data for Anova and correlation coefficient. Results: Mean age was 29years, it showed participating to the classes and subjects ages had no significant relation ship, but the level of education showed a significant relationship with knowledge about AIDS, but not significant in hepatitis B. 76 percents of the subjects had a good knowledge of AIDS and 58 percent of people were also aware to hepatitis B.

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Introduction: Kawasaki disease happens mostly in children less than 5 years of age and presents itself as an acute and self-limiting disease with world wide spread. One of the important consequences of this disease, if undetected, is the cardiovascular morbidity that caused by the disease. The aim of this study was to determine demog-raphic findings about cardiovascular afflict-tions in Kawasaki patients. Materials & Methods: The study was a descriptive and retrospective study and data were provided through reviewing of medi-cal records of Kawasaki patients who had been hospitalized between 1998 to 2003 at Imam Hossein and Mofid Children's Hosp-ital. Finding: In the aforementioned period, 97 patients with Kawasaki disease were hospit-alized in two centers, 65(67.1%) males and 32(32.9%) female). 75(77.3%) patients we-re under the age of 5 years and 22(22.7%) were older than 5 years. 32(32.9%) patients had one or more heart involvements. The number of patients with heart involvements were 20 males (62.5%) and 12 females (37.5%). The most heart involvements were pericardial effusion (23.7%) and the least heart involvements were coronary artery dilation and aortic stenosis(2%). Discussion & Conclusions: Timely diagn-osis and preventive treatment can prevent the complications of Kawasaki disease. The cardiac rehabilitation program could impro-ve the life quality of the patients

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educational media has been considered to provide information and skills necessary for healthy decision-making and community h-ealth promotion. Therefore, evaluation of health education media is essential to impr-ove and promote the quality of health edu-cation. Materials & Methods: The study samples included all produced media in all Iran me-dical universities, offices, and centers affili-ated to the ministry of health during 2005 to 2010. All of the media under investigation were categorized by type and topic through software that was designed for this purpose and then, they were analyzed. Findings: Results of this study showed that 16.44% of the media produced in the com-municable diseases subject and 13.33% produced in the non-communicable subject. Pamphlet had the highest percentage of the media (34.91%) and Multimedia had the lowest percentage (0.0001%). Study findi-ngs also showed that the non-print media comprised only 6% of the mass media. Discussion & Conclusion: Given the imp-ortant role of educational media, especially new media in Increasing the knowledge and community empowerment, it is recomm-ended to paid more attention to the neces-sity of new media to inform health educa-tors.

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Introduction: Psychological stress in work-place is among the stress-inducing factors that influence the workers’ health and dam-age their occupational performance and sa-fety. The present study was carried out to investigate the relationship between general health and workers’ sleep quality as well as the work safety in Gole Gohar Mineral Ind-ustries Co., Sirjan, Iran. Materials & Methods: The present cross-sectional and descriptive-analytical study was carried out in 2011-2012. The statist-ical population included 337 workers in Hematite and Pelletizing section in Gole Gohar Mineral Industries Co., Sirjan in Iran. The sampling was carried out in a simple random selecting method. A general health questionnaire having 28 questions (GHQ) and the Pittsburg Sleep Quality In-dex (PSQI) were applied in the study. Anal-yses of data were carried out using SPSS 19 software and descriptive and inferential statistics tests. Findings: The average age of workers was 30.92±4.78 years and their working experi-ence averaged 5.47±3.24 years. 82.9 perc-ent of the workers responding to the questi-onnaire were satisfied with their jobs, and 17.1 percent were not satisfied. Using 23- point break in large-scale and 6- point break in small-scale, psychological disorders were detected in 29.4 percent of workers. Also, 46.9 percent of the workers experienced satisfactory sleep and 53.1 percent of them experienced unsatisfactory sleep. Discussion & Conclusion: With the high incidence of industrial accidents in Iranian industrial environments, the workers’ health must be regarded as a prime necessity. The results of the present study could provide valuable information about the treatment and prevention of psychological disorders for policy-makers and relevant authorities

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Introduction: Cardiomyopathies are referr-ed to those diseases accompanied with he-arth dysfunction which the most common of them is dilated cardiomyopathy. This study aimed to evaluate the clinical sympt-om, prognosis, complications, treatment and mortality in patients with cardiomyo-pathy over a 10 years period. Materials & Methods: In this retrospective descriptive study, all patients had been dis-charged with the final diagnosis of dilated cardiomyopathy and referred to the Rajaee Hospital in Tehran, Iran during the past 10 years were studied. The necessary data of each patient was individually collected. Data analysis was performed using descrip-tive and inferential statistical tests. Findings: From 87 patients in the study, 54 (54%) and 40 (46%) patients were female and male, respectively. The most common reason of referring to the Hospital was dys-pnea (70%) and the most common clinical finding was systolic murmur 3.6 in the left corner of sternum. The blood group of most patients was B+. There were a big heart in the radiography of chest, left ventricular di-latation in echocardiography, reduced left ventricle contractility in catheterization (EF=35%). The most common complicat-ions in the patients were mitral valve reg-urgitation and left heart failure. The embo-lism was reported as a rare complication. In evaluation of the relationship between pres-cribed medications and prognosis, the digi-talis compounds, Lasix and Aldacton (with 2 died patients), were the most prescribed medications. The three above drugs along with Hydralazine had been led to the death of 1 patient. Discussion & Conclusion: According to the results of the study, it is appeared that the type of blood group may predispose subje-cts to dilated cardiomyopathy. Overcrowde-d environment and air pollution may incre-ase the incidence of the disease the presc-ribed medications may influence the prong-osis and mortality of the diseases.

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Background and Objectives Chromium is a common contaminant in ground and surface water, soil and waste water. Chromium is of considerable because of toxicity and environmental and human health. The aim of this research were to synthesize magnetite nanoparticles (Fe3O4) and determining its efficiency in chromium removal from aqueous solutions. Materials and Methods: magnetite nanoparticles were synthesized and the effects of pH and contact time on cadmium removal efficiency were investigated in batch system. Then kinetics and isotherm models coefficients were determined based on optimum conditions. Scanning Electron Microscopy (SEM), XRD were used to characterization of the synthesized magnetite nanoparticles. Results: SEM results showed that the diameter of the particles is 40-50 nm. Results showed that the optimum pH value for chromium adsorption was 2 and the equilibrium time was 60 min. The magnetite nanoparticles have advantages such as high removal efficiency and short reaction time and can be used as a method to remove cadmium from aqueous solutions. The adsorption kinetics fitted using the type1- pseudo second-order kinetic model and the adsorption isotherm could be described by the langmuer. The langmuer maximum adsorption capacity of magnetite nanoparticles for Cr(VI) was found to be 24 mgg-1. Conclusion: These results indicated that magnetite nanoparticles can be employed as an efficient adsorbent for the removal of chromium from contaminated water sources. The results also revealed that the magnetite nanoparticles supported have a better adsorption capacity, better magnetic properties and separation, and therefore, lower cost.

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Abstract

Introduction: Water treatment by membrane methods such as reverse osmosis is used by people in the region that the quality of drinking water is not suitable. The low quality of water in Abadan city is resulted in the use of water treatment centers with reverse osmosis (RO) systems and distribution of water by portable tanks over the city. In this study, the microbial quality of product water supplied by the treatment centers and portable water tanks was examined.

Materials and Methods: This cross-sectional study was conducted in the water treatment centers and portable water tanks over six months (summer and autumn 2012) in Abadan city. A total of 159 samples were taken and examined by the standard procedures. The parameters of E.coli, coliform, TDS, EC, pH, residual chlorine and turbidity were measured in this work.

Results: The results showed that 2% of water treatment centers and 5% of portable tanks were contaminated by E.coli microorganism. The residual chlorine and turbidity of water samples were also undesirable in the 92% and 87% of the tested samples, respectively. But, the results of the EC, TDS and PH analysis of the water samples showed that the quality of these parameters were in the range of the national and international standards.

Discussion and Conclusion: Despite more microbial contamination of water in the portable water tanks toward the water treatment centers, the statistical analysis did not show the significant difference between them (P-value>0.05). But, due to the high microbial contamination observed in the portable tanks, the adding the disinfectants into the water tanks and educating the portable tanks operators to rise of their awareness can be effective in reducing the secondary bacterial infections.

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Introduction: Practical Application of Intimate Relationship Skills program is a marriage enrichment program which notifies couples to realize the importance of intimate relationships through putting emphasis on the need for intimacy. The present study was conducted by the aim of investigating the effect of group training based on practical application of intimate relationship skills program on marital relationship quality.

Materials & methods: The current study used a quasi-experimental method with pretest-posttest with control group design. The population of the study consisted of all the couples visiting Golha health house in the 6th district of Tehran in 2013. The sample included 20 couples who were selected by available sampling method, and were randomly assigned to experiment and control groups (10 pairs each). The research tool was The Golombok-Rust Inventory of Marital Status (GRIMS, 1998) which was completed by the participants in the pre-test and post-test phases. Practical application of intimate relationship skills program was performed in thirteen 1.5 hour sessions for couple of the experiment group, but the control group received no intervention.

Findings: The results of univariable covariance analysis indicated that practical application of intimate relationship skills program promoted the quality of marital relationship in the couples of the experiment group, compared to the control group at posttest (F=46.43, P=0/000).

Discussion & Conclusions: The practical application of intimate relationship skills is effective in improving the quality of marital relationships. This program can be used as a marriage enrichment program for the purpose of preventing problems and improving couples’ relationships. 

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Introduction: Breast cancer is the most common malignancy in women, causing high mortality in the affected patients. The identification of circulating tumor biomarkers in blood could be considered as non-invasive strategy for early diagnosis and prognosis. The aim of this study was to investigate the presence of PRNCR1 (prostate cancer associated non-coding RNA 1) gene in the plasma of patients with breast cancer and to evaluate its expression compared to the normal ones.

Materials & Methods: This study was carried out on the 32 blood samples from breast cancer patients and 25 ones from healthy women. The RNA was extracted from the plasma of the samples. Subsequently, the presence of RNA of PRNCR1 gene in plasma of patients was quantitatively evaluated by a real-time polymerase chain reaction (Real-Time PCR). Moreover, the expression of PRNCR1 gene was studied in terms of clinico-pathological characteristics of patients. The statistical analysis of data was performed in SPSS software using  t-test.

Findings: The results showed that the PRNCR1 gene could be detected in the plasma of cancer patients. The obtained results indicated significantly higher expression in tumor samples, compared to the healthy ones (P<0.05). However, statistical data showed that the expression of PRNCR1 gene in tumor samples does not have any significant correlation with clinical-pathological characteristics, including tumor size, age, and lymph node involvement (P>0.5).

Discussion &Conclusions: The data demonstrated that circulating non-coding PRNCR1 of plasma could be used in the discrimination of breast invasive ductal carcinomas from those of normal people. However, more studies should be conducted to determine the tumorigenic role of lncRNA PRNCR1. 

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Introduction: Long non-coding RNAs (lncRNAs) and miRNAs belong to a class of non-coding RNAs (ncRNAs) that play important roles and functions in the regulation of the expression of genes in main biological processes, such as cell proliferation, apoptosis, and differentiation. LncRNAs can potentially affect miRNAs in the forms of cis/trans to modulate their regulatory role. In this study, mRNA, miRNA, and lncRNA gene networks were predicted by web-based programs for three ectodermal pathway markers (BMP4, NOG, FGF8) in the mouse embryonic stem cells.
Material & Methods: In this theoretical bioinformatics study, the miRNAs of the target genes (BMP4, NOG, and FGF8) were extracted and examined by MirWalk and TARGETSCAN databases to finally obtain the common miRNAs of these three genes. Following that, the target lncRNAs for common miRNAs were then extracted from the DIANA-Tool database.
(Ethic code: 100/21560/2/پ)
Findings: MiRs mmu-miR-92a-2-5p, mmu-miR-129b-5p, mmu-miR-130b-5p, mmu-miR-692, mmu-miR-7009-3P, mmu-miR-7116-3p, and mmu-miR-7689-3p may affect the function of lncRNAs, including Kcnq1ot1, Gm26812, Gm4117, Gm11837, 4930423MO2Rik, Malat1, Gm12594, Gm3414, 5830444B04Rik, Gm2464, and NEAT1.
Discussion & Conclusion: Due to the mutual relationships among lncRNA, miRNA, and mRNA, our results provided a novel perspective on lncRNAs for future research and experimental studies on ectodermal differentiation pathways and molecular mechanisms.
 

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Introduction: Leishmaniasis is one of the six infectious diseases emphasized by the World Health Organization. Mehran and Dehloran cities in the south of Ilam province are endemic centers of cutaneous leishmaniosis in the country. Ilam Province, having near to 420 km common border with Iraq, is exposed to many zoonotic and tropical diseases, including Cutaneous leishmaniasis. Therefore, prevention, early diagnosis and treatment are essential. The registration program is an inseparable and necessary component of comprehensive patient care systems, which can be used as a tool to show the status of the disease. By providing sufficient data, this program has a useful role for managers to use in health care planning. Registry is a necessary component of comprehensive patient care systems, which can be used as a tool to show the status of the disease, which is called follow-up.
Material & Methods: The aim of Cutaneous leishmaniasis registration program in the endemic areas of Ilam province is collection and comparing the correct methods of diagnosis disease with the common one (microscopy) and determining the number of errors made by laboratory experts in the form of a cross-sectional study from May 2018 to august It is 2020.
Findings: By using molecular tests (PCR) to 10% of all positive slides received from Dehloran and Mehran cities, about 5% were false positives, and 28% of all negative slides collected was false negative. It should be mentioned that the implementation of the registration program in Ilam province during the epidemic of corona disease.
Discussion & Conclusion: According to the findings of this study and the importance of the disease due to its endemicity in the southern part of Ilam province, the presence of increasing prevalence of the disease in the past years, the relation between of the traffic of Arbain Hosseini pilgrims with the period of transmission of the disease, mental and physical complications caused by the disease, it is recommended to ensure the referral diagnosis reports of health and laboratory experts, and apply the correct method of diagnosis and reporting, elimination of suspicious, positive and false negative result, and start a molecular diagnosis center, that can help patients be followed up with the correct diagnosis until the of recovery of the treatment period.