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:: Volume 32, Issue 5 (12-2024) ::
Journal of Ilam University of Medical Sciences 2024, 32(5): 14-22 Back to browse issues page
Investigating the relationship between coagulation indices and mortality in patients with COVID-19 hospitalized in the intensive care unit of Dezful Ganjavian hospital in 2020
Mahin Behzadifard * 1, Zahra Eslamifar2 , Yasin Arianezhad3 , Nooshin Asadmasjedi2 , Behnam Azizolahi2 , Maziyar Heydari4
1- Dept of Laboratory Sciences, Faculty of Paramedicine, Dezful University of Medical Sciences, Dezful, Iran , mahinbehzadi2020@gmail.com
2- Dept of Laboratory Sciences, Faculty of Paramedicine, Dezful University of Medical Sciences, Dezful, Iran
3- Student Research Committee of Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
4- Student Research Committee, Dezful University of Medical Sciences, Dezful, Iran
Abstract:   (153 Views)
Introduction:  Many factors, including coagulation disorders, have an effect on mortality in patients with Covid-19 viral infection. Considering coagulation problems are so important for these patients, the goal of this study was to look into the connection between coagulation test results, such as prothrombin time (PT), partial thromboplastin time (PTT), D-dimer, and platelet count, and the death rate in Covid-19 patients who were admitted to the intensive care unit of Ganjovian Hospital (Dezful, Iran) in 2020.
Materials & Methods: This comprehensive cross-sectional study was conducted on the information of 100 patients with Covid-19 hospitalized in the intensive care unit. The data from the patient’s files were analyzed using Graph Pad Prism version 8.3 statistical software. Qualitative variables were described using frequency indices, percentages, and relative frequency. A t-test was also used to compare the study parameters between the death and discharge groups. The level of significance was considered less than 0.05.
Results: The mean and standard deviation of the age were 58.2±14.2. The average age of the death group was significantly higher than that of discharged patients (P=0.038). The D-dimer and PT test results in patients with Covid-19 who died were significantly higher than those of discharged patients (P=0.002), but there was no significant difference in platelet count and PTT between the two groups (P=0.680).
Conclusion: According to the results of this study, paying attention to the results of D-dimer and PT tests may be helpful in predicting the prognosis of Covid-19 disease.
 
Keywords: Covid-19, SARS-CoV-2, nSARS-CoV-2, D-dimer, Prothrombin time, Relative thromboplastin time, Platelet count, Intensive care unit, ICU
Full-Text [PDF 722 kb]   (96 Downloads)    
Type of Study: Research | Subject: virology
Received: 2024/04/13 | Accepted: 2024/05/21 | Published: 2024/12/5
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Behzadifard M, Eslamifar Z, Arianezhad Y, Asadmasjedi N, Azizolahi B, Heydari M. Investigating the relationship between coagulation indices and mortality in patients with COVID-19 hospitalized in the intensive care unit of Dezful Ganjavian hospital in 2020. J. Ilam Uni. Med. Sci. 2024; 32 (5) :14-22
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Volume 32, Issue 5 (12-2024) Back to browse issues page
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