[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Journal Information::
Articles archive::
Publication Ethics::
Peer Review Process::
Indexing Databases::
For Authors::
For Reviewers::
Contact us::
Site Facilities::
Google Scholar Metrics

Citation Indices from GS

AllSince 2019

Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Registered in



:: Volume 19, Issue 4 (1-2012) ::
Journal of Ilam University of Medical Sciences 2012, 19(4): 20-25 Back to browse issues page
Comparison Between Remifentanil And Fentanyl Effects on
A.R Purnajafian * 1, S Ghavam , S Ghavam , M.R Hafezi Ahmadi , M Ghavam
1- , drpournajafian@iums.ac.ir
Abstract:   (33260 Views)
Introduction: Intravenous opioid injection as premedication is one of the most common methods for preventing and controlling hemodynamic changes due to laryngoscopy and tracheal intubation. Using such drugs is not suggestsd in pregnant women who candidate for cesarean section, because of respiratory depression in the newborn, but in special conditions such as preeclampsia, anesthetists can inject low doses of fentanyl(as a synthetic opioid). Because of rapid metabolism of remifentanil and no respiratory effects in the newborn, it can be introduced as a perfect alternative for longer acting opioids in such conditions. Materials & Methods: This study was done as a randomized clinical trial on preeclamptic pregnant women who were candidate for cesarean section under general anesthesia. They were divided into two groups: in one group 1ml. fentanyl was injected before induction of anesthesia(n1=18) , and in the other group 0.05 g/kg/min remifentanil was infused for 3 minutes before induction (n2=20). Afterwars, of heart rate, systolic and diastolic blood pressures before and after intubation and also the newborn's apgar were measured and assessed. Findings: All hemodynamic indices increased after intubation in the fentanyl group , and increase in diastolic pressure an heart rate was significant. Mild increase in heart rate and decreasing in systolic and diastolic blood pressure after intubation in remifentanil group was achieved that the decrease in systolic blood pressure was significantly different(R1=154.35, R2=148.35). Comparison of changes between the two groups also demonstrated significant difference (Pval.<0.05). The newborns mean apgar score showed no signifant difference between the two groups(AP.remi=0.88, AP.fent=0.86). Discussion and Conclusion: Considering no difference between the newborns apgar in both the groups and results of assessment of hemodynamic indices, it can be suggested to use remifentanyl in pregnant women who are candidate for cesarean section under general anesthesia to prevent severe increase in blood pressure and heart rate during tracheal intubation.
Keywords: cesarean section, preeclampsy
Full-Text [PDF 155 kb]   (3984 Downloads)    
Type of Study: Research | Subject: General
Received: 2012/03/13 | Published: 2012/01/15
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Purnajafian A, Ghavam S, Ghavam S, Hafezi Ahmadi M, Ghavam M. Comparison Between Remifentanil And Fentanyl Effects on. J. Ilam Uni. Med. Sci. 2012; 19 (4) :20-25
URL: http://sjimu.medilam.ac.ir/article-1-566-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 19, Issue 4 (1-2012) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
Persian site map - English site map - Created in 0.14 seconds with 41 queries by YEKTAWEB 4646