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Positive and negative false results of tuberculin test in diagnosing pericardial tuberculosis in Emam Khomeini and Modaress hospitals of Tehran (2004-4)
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Abstract: (20462 Views) |
| Abstract
Introduction: Mycobacterium tuberculosis. Is one of the most common factors which causes pericarditis following suffering from lung tuberculosis. To diagnose pericarditis caused by mycobacterium tuberculosis , methods like PPD test, culture and staining of pericardial fluid , biopsy of pericardial tissue and PCR of pericardial fluid are used. In this study, level of specific sensitivity of PPD test for diagnosis of pericardial tuberculosis has been evaluated.
Materials&Methods: 100 patients admitted at the academic hospitals of Shahid Behshti and Iman Khomaini medical universities underwent experimental observations for diagnosis of primary pericardial tuberculosis during 1981-4. First PPD test was done, then a sampling of pericardial fluid and biopsy of pericardial tissue were accomplished. The pericardial was used for fluid staining by Ziehl-Neelsen and culture on Leuin – Estein Jonson media. After fixation and H&E staining, the necessary studies continued to consider the cheesy granuloma and tuberculosis bacilli.
Findings: In this study, out of the 100 selected patients, 40 cases were diagnosed as suffering from pericardial tuberculosis by laboratory tests, all the cases were complaining of tuberculosis symptoms. Culture of pericardial fluid in 18 patients (45%), and pericardial biopsy in 18 ones (45%), staining of pericardial fluid in 9 patients (22.5%) and tuberculin cutanous test in 30 patients (75%) proved positive, while false negative cutanous tuberculin test in 10 patients (25%) and false positive results in (45%) of patients were significantly were achieved |
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| Keywords: mycobacterium tuberculosis, tuberculin test, Leuin-Estein culture |
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Full-Text [PDF 469 kb]
(4554 Downloads)
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Type of Study: Research |
Subject:
General
Received: 2009/01/27 | Accepted: 2015/04/21 | Published: 2015/04/21
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