Introduction: Majority of researches have referred to reduction of stress oxidative, during consumption of antioxidant supplements or exercise training. The aim of the present study, was to investigate "the effect of endurance swimming training plus consumption of vitamin C supplement, on the indices of oxidative stress among male wistar rats".

Materials & methods: Twenty four male wistar rats weighing 250 to 300 g, were randomly divided into four groups:1-Taining (T), 2- Training plus vitamin C (T &VC), 3- control (C), and 4- control plus vitamin C (C &VC).Training groups participated in a swimming program 5 d/w, 1 h/d, for ten weeks. Using vitamin C supplement (100 mg/kg) ) started one week before starting training protocol, and continued to the end of tenth week. One day after the end of training protocol, sampling blood of rats were obtained to measure the indices of oxidative stress including malondyaldehyde (MDA), catalase (CAT), uric acid (U.A), and total antioxidant capacity (TAC). Results were analyzed using the one-way ANOVA followed by a Tukey test. Significance level was 0.05.

Findings: The results of this research indicate that T &VC significantly reduced the level of MDA in comparison to C group (P = 0.008). A significant increase in the level of TAC was also observed in C &VC group in comparison to T group (P = 0.01). But there was no significant difference in the level of CAT and U.A.

Discussion & conclusions: In conclusion, results of the current study indicates that consumption of VC may decrease the lipid peroxidation and increase the level of TAC, while it did not affect CAT and U.A antioxidants.