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:: Volume 21, Issue 6 (12-2013) ::
Journal of Ilam University of Medical Sciences 2013, 21(6): 134-145 Back to browse issues page
X-linked Hyper-IgM Syndrome: Control and Treatment
A Khalil nejad , E Mahmodian , A Khalil nejad , R Roghanian , A Etedali , R Vafaee * 1, M Hosainzade
1- , Vafaeereza@gmail.com
Abstract:   (13349 Views)
X-linked hyper-IgM syndrome (XHIGM) is a congenital immunodeficiency in which the immune system cannot produces differ-rent classes of immunoglobulins other than IgM. Therefore, the patients are susceptible to many disorders, infectious diseases and malignancies. Bone marrow or allogeic he-matopoietic cell sorcord blood stem cells transplantation are the two accepted ther-apeutic approaches to treat patients with XHIGM. In addition, various numbers of interventions including IVIG and SCIG therapy, antimicrobial agents and etcare used to control and prevent the XHIGM-related diseases and conditions. In the present manuscript, we review all of these approaches.
Keywords: anaphylaxis, antibody therapy, bone marrow transplantation, primary imm-uneodeficiency, stem cell transplantation
Full-Text [PDF 383 kb]   (5520 Downloads)    
Type of Study: Research | Subject: immunology
Received: 2014/01/4 | Accepted: 2014/01/4 | Published: 2014/01/4
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khalil nejad A, mahmodian E, khalil nejad A, roghanian R, etedali A, vafaee R et al . X-linked Hyper-IgM Syndrome: Control and Treatment. J. Ilam Uni. Med. Sci. 2013; 21 (6) :134-145
URL: http://sjimu.medilam.ac.ir/article-1-1478-en.html

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Volume 21, Issue 6 (12-2013) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
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