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Effect of Fasting on Fasting Blood Glucose, Lipid Profile and Liver Enzymes
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E Ghasemi   , F Noor abadi , Ar Baziar , M Yasemi , S Ehsan bakhsh , M Rashid begi * 1 |
| 1- , miladrashidbeygi@yahoo.com |
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Abstract: (13919 Views) |
| Introduction: More than 400 million of Muslims deal with fasting during the fasting month of Ramadan. Given the high prevalence of diabetes, lipid disorders, and abnormalities in liver enzyme levels and also the presence of contradictions about the effect of Ramadan fasting on metabolic parameters, we decided to assess the effect of Ramadan fasting on the above metabolic indices.
Materials & Methods: The before and after study was carried out on 120 subjects referred to the Mustafa hospital in Ilam city during 2012. All subjects were included into research according to ethical standards and after signing a written informed consent. People who were not fasting during Ramadan excluded from the study and the sample size was designed to be 98 subjects. Before and the days of Ramadan, the metabolic indices (fasting blood glucose, triglycerides, total cholesterol, LDL, HDL and liver enzymes) were measured. The indices were measured by BT3000 instrument and the paired t-test was used to analyze data.
Finding: The mean levels of alanine transaminase (ALT) enzyme were 17.44±23.15 U/mL before Ramadan and 34.85±29.32 U/mL after Ramadan, which their difference was statistically significant (P=0.02). The mean levels of LDL were 25.84±106 mg/dL before Ramadan and 22.12±94.99 mg/dL after Ramadan, which their difference was statistically significant (P=0.000). The mean levels of glucose were 85.54±12.25 mg/dL before Ramadan and 85.17±13.97 mg/dL after Ramadan, which their difference was not statistically significant (P=0.07).
Discussion & Conclusion: In the study, the mean levels of triglyceride, LDL and HDL reduced but significant increase in ALT was created after fasting. No significant difference was found between the glucose levels before and after Ramadan. And total cholesterol levels were significantly increased after Ramadan. |
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| Keywords: fasting glucose, triglycerides, total cholesterol, LDL and HDL |
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Full-Text [PDF 399 kb]
(4365 Downloads)
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Type of Study: Research |
Subject:
Internal operations( nursing )
Received: 2013/10/14 | Accepted: 2013/10/15 | Published: 2013/10/15
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