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:: Volume 32, Issue 3 (8-2024) ::
Journal of Ilam University of Medical Sciences 2024, 32(3): 85-100 Back to browse issues page
Analysis of Personality and Lifestyle in Slow-Paced Adults with Down Syndrome with and without Alzheimer's Disorder
Maryam Kazemi1 , Gholamali Afrooz * 2, Keyvan Kakabaraee3 , Maryam Asaseh1 , Mohamad Parsa Azizi1
1- Dept of Psychology and Exceptional Children, Faculty of Literature, Humanities and Social Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran
2- Dept of Psychology and Exceptional Children, Tehran University, Tehran, Iran , afrooz@ut.ac.ir
3- Dept of Psychology and Exceptional Children, Faculty of Literature and Humanities, Islamic Azad University, Kermanshah Branch, Kermanshah, Iran
Abstract:   (491 Views)
Introduction:  Down syndrome is the most common chromosomal disorder. Alzheimer's disease is the most prevalent disease affecting these individuals from middle age onwards and leading to numerous problems for individuals, their families, and their caregivers. To develop Alzheimer's prevention strategies for Down syndrome, it is of utmost importance to understand the factors that contribute to its development, such as psychological foundations. The present study aimed to analyze personality and lifestyle in slow-paced adults with Down syndrome with and without Alzheimer's disease.
Material & Methods: This qualitative research was conducted based on a descriptive phenomenological design. The research population consisted of adults with Down syndrome (60 cases without Alzheimer's and 10 subjects with Alzheimer's), their parents, and caregivers in Kermanshah province in 2023. In this regard, data collection was carried out through access to medical records of individuals in the Welfare Organization and also semi-structured interviews with these individuals who were purposefully selected until reaching the stage of theoretical saturation. Data analysis was performed using the Clausi method, and the main and sub-themes were identified. For final validation, the criteria of validity and reliability were used.
Results: The findings from the data analysis resulted in the extraction of 3 main themes (social-psychotic-coping skills), 14 sub-themes in personality dimension, and 9 main themes (sleep-physical activity-occupation-physical health-weight control and nutrition-personal hygiene-smoking and alcohol consumption-leisure time-doing things independently) and 21 sub-themes in the lifestyle dimension.
Discussion & Conclusion: The results of this study highlighted the role and importance of a healthy lifestyle and adaptive personality characteristics in preventing Alzheimer's disease in slow-paced adults with Down syndrome. Therefore, it is suggested that preventive and awareness-raising programs in these two dimensions be developed and implemented by experts and official centers.

Keywords: Alzheimer, Down syndrome, Lifestyle, Personality, Phenomenology
Full-Text [PDF 1288 kb]   (277 Downloads)    
Type of Study: Research | Subject: psychology
Received: 2024/03/7 | Accepted: 2024/05/27 | Published: 2024/08/5
References
1. Antonarakis SE, Skotko BG, Rafii MS, Strydom A, Pape SE, Bianchi DW, et al. Down syndrome. Nat Rev Dis Primers 2020; 6: 1-43. doi:10.1038/s41572-019-0143-7.
2. Centers for Disease Control and Prevention. Facts about down syndrome. National Center on Birth Defects and Developmental Disabilities. 2022 [Available from: https://www.cdc.gov/birth-defects/data-research/facts-stats/index.html.
3. Capone G, Stephens M, Santoro S, Chicoine B, Bulova P, Peterson M, et al. Co‐occurring medical conditions in adults with Down syndrome: A systematic review toward the development of health care guidelines. Part II. Am J Med Genet A 2020; 182:1832-45. doi: 10.1002/ajmg.a.61604.
4. Lemoine L, Ledreux A, Mufson EJ, Perez SE, Simic G, Doran E, et al. Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue. Mol Neurodegener 2020; 15: 68. doi: 10.1186/s13024-020-00414-3.
5. Pavisic IM, Pertzov Y, Nicholas JM, O'Connor A, Lu K, Yong KX, et al. Eye-tracking indices of impaired encoding of visual short-term memory in familial Alzheimer's disease. Sci Rep 2021; 11: 8696. doi: 10.1038/s41598-021-88001-4.
6. Afrooz G, Nosrati F. Down syndrome. Tehran: Tehran University Publications; 2022.
7. Ghai R, Nagarajan K, Arora M, Grover P, Ali N, Kapoor G. Current strategies and novel drug approaches for Alzheimer disease. CNS Neurol Disord Drug Targets 2020; 19: 676-90. doi: 10.2174/1871527319666200717091513.
8. Lanyau-Domínguez Y, Macías-Matos C, Llibre-Rodríguez JdJ, Pita-Rodríguez GM, Suárez-Medina R, Quintero-Alejo ME, et al. Levels of vitamins and homocysteine in older adults with Alzheimer disease or mild cognitive impairment in cuba. MEDICC Rev 2020; 22: 40-7. doi: 10.37757/MR2020.V22.N4.14.
9. Landes SD, Stevens JD, Turk MA. Cause of death in adults with Down syndrome in the United States. Disabil Health J 2020; 13: 100947. doi: 10.1016/j.dhjo.2020.100947.
10. Bejanin A, Iulita MF, Vilaplana E, Carmona-Iragui M, Benejam B, Videla L, et al. Association of apolipoprotein E ɛ4 allele with clinical and multimodal biomarker changes of Alzheimer disease in adults with Down syndrome. JAMA Neurol 2021; 78: 937-47. doi: 10.1001/jamaneurol.2021.1893.
11. Pape SE, Baksh RA, Startin C, Hamburg S, Hithersay R, Strydom A. The association between physical activity and CAMDEX-DS changes prior to the onset of Alzheimer's disease in Down Syndrome. J Clin Med 2021; 10: 1882. doi: 10.3390/jcm10091882.
12. Yañez AM, Bennasar-Veny M, Leiva A, García-Toro M. Implications of personality and parental education on healthy lifestyles among adolescents. Sci Rep 2020; 10: 7911. doi: 10.1038/s41598-020-64850-3.
13. Ijezie OA, Healy J, Davies P, Balaguer-Ballester E, Heaslip V. Quality of life in adults with Down syndrome: A mixed methods systematic review. PLoS One 2023; 18: e0280014. doi: 10.1371/journal.pone.0280014. eCollection 2023.
14. Alrayes N, Issa NM, Alghubayshi OY, Al‐Amaa JY, Alsabban AH, Al Shaer DS, et al. Quality of life in children with Down syndrome and its association with parent and child demographic characteristics: Parent‐reported measures. Mol Genet Genomic Med 2024; 12: e2337.doi: 10.1002/mgg3.2337. Epub 2023 Dec 13.
15. Hamadelseed O, Elkhidir IH, Skutella T. Psychosocial risk factors for Alzheimer's disease in patients with down syndrome and their association with brain changes: a narrative review. Neurol Ther 2022; 11: 931-53. doi: 10.1007/s40120-022-00361-9. Epub 2022 May 21.
16. Omidi Khankahdani M, Afrooz GA, Ghasemzadeh S, Naghsh Z. Factors Affecting the Quality of Life in Families of Children with Down Syndrome: The Lived Experience of Families and Professionals. Psychology of Exceptional Individuals. J Psyc Except Indi 2023;13:1-28. doi:10.22054/jpe.2022.65939.2417.
17. Bahiraei S, Daneshmandi H, Amiri R. Physical Fitness and Health-Related Physical Activity Programs in People With Down Syndrome: A Systematic Review. J Sport Biomech 2020; 5: 200-15. doi:10.32598/biomechanics.5.4.1.
18. Mohammadi A, Asgharzadeh M. Relationship between cognitive distortions and dysfunctional attitudes and personality traits in students. J Analitical-Cognitive Psyc 2017; 8: 23-32.
19. Ostadhasanloo H, Mahmoodi F, Adib Y, Zamanzadeh V. Lived Experiences of Nursing Students Concerning Education in Simulated Learning Environments: A Phenomenological Study. J Med Educ Dev 2022; 15:68-76. doi:10.52547/edcj.15.45.68.
20. Nolen-Hoeksema S, Fredrickson B, Loftus G, Wagenaar WA. Atkinson & Hilgard's introduction to psychology. translation by: Rafiei H, Arjmand M. Tehran: Arjmand Publications. 2015.
21. Ruthirakuhan M, Luedke AC, Tam A, Goel A, Kurji A, Garcia A. Use of physical and intellectual activities and socialization in the management of cognitive decline of aging and in dementia: a review. J Aging Res 2012: 2012: 384875. doi: 10.1155/2012/384875.
22. Qiu C, Kivipelto M, Von Strauss E. Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention. Dialogues Clin Neurosci 2009; 11: 111-28. doi: 10.31887/DCNS.2009.11.2/cqiu.
23. Fonseca LM, Mattar GP, Haddad GG, Burduli E, McPherson SM, Guilhoto LMdFF, et al. Neuropsychiatric symptoms of Alzheimer's disease in Down syndrome and its impact on caregiver distress. J Alzheimers Dis 2021; 81: 137-54. doi: 10.3233/JAD-201009.
24. Bishop A, Younan R, Low J, Pilkington PD. Early maladaptive schemas and depression in adulthood: A systematic review and meta‐analysis. Clin Psychol Psychother 2022; 29: 111-30. doi: 10.1002/cpp.2630.
25. Maleki Samian L, Afrooz G, Gholamali Lavasani M, Bahrami H. Comparison of Personality Traits and Working Memory in Slow-Moving Adults with Down Syndrome and without Alzheimer's Disorder in Tehran and Baku. J Excellence counseling psych 2020; 9: 57-68.
26. Dekker AD, Ulgiati AM, Groen H, Boxelaar VA, Sacco S, Falquero S, et al. The behavioral and psychological symptoms of dementia in down syndrome scale (BPSD-DS II): Optimization and further validation. J Alzheimers Dis 2021; 81: 1505-27. doi: 10.3233/JAD-201427.
27. Rivelli A, Fitzpatrick V, Chaudhari S, Chicoine L, Jia G, Rzhetsky A, Chicoine B. Prevalence of mental health conditions among 6078 individuals with Down syndrome in the United States. J Patient Cent Res Rev 2022; 9: 58-63. doi: 10.17294/2330-0698.1875.
28. García-Alberca JM. Cognitive-behavioral treatment for depressed patients with Alzheimer's disease. An open trial. Arch Gerontol Geriatr 2017: 71:1-8. doi: 10.1016/j.archger.2017.02.008.
29. Darla S, Bhat D. Health-related quality of life and coping strategies among families with Down syndrome children in South India. Med J Armed Forces India 2021; 77: 187-93. doi: 10.1016/j.mjafi.2020.07.010.
30. Fortea J, Zaman SH, Hartley S, Rafii MS, Head E, Carmona-Iragui M. Alzheimer's disease associated with Down syndrome: a genetic form of dementia. Lancet Neurol 2021; 20: 930-42. doi: 10.1016/S1474-4422(21)00245-3.
31. Ahmadi Y, Ganji M, Mohamadi MS. Meta-Analysis of Lifestyle's Studies in Iranian Research. Socio Lifest Manage 2020; 5: 1-37. doi: 20.1001.1.24237558.1400.6.2.1.6.
32. Chen C-CJ, Ringenbach SD. Parental Report of Physical Activity and Sleep in Individuals with Down Syndrome. J Dev Physic Disabil 2023; 35: 375-86. doi:10.1007/s10882-022-09855-8.
33. Wissing MB, Ulgiati AM, Hobbelen JS, De Deyn PP, Waninge A, Dekker AD. The neglected puzzle of dementia in people with severe/profound intellectual disabilities: A systematic literature review of observable symptoms. J Appl Res Intellect Disabil 2022; 35: 24-45. doi: 10.1111/jar.12920.
34. Khanahmadi M, Farhud D, Malmir M, Orang S. Genetically Overlap of Down Syndrome and Alzheimer's Disease. J Except Child 2016; 15: 29-36.
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Kazemi M, Afrooz G, Kakabaraee K, Asaseh M, Azizi M P. Analysis of Personality and Lifestyle in Slow-Paced Adults with Down Syndrome with and without Alzheimer's Disorder. J. Ilam Uni. Med. Sci. 2024; 32 (3) :85-100
URL: http://sjimu.medilam.ac.ir/article-1-8254-en.html


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Volume 32, Issue 3 (8-2024) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
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