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:: Volume 33, Issue 2 (5-2025) ::
Journal of Ilam University of Medical Sciences 2025, 33(2): 1-12 Back to browse issues page
Implementation of MLC-based techniques for kidney protection as isolated organs during radiotherapy of abdominal malignancies
Warya Parvaii1 , Ghazal Mehri-Kakavand2 , Tahereh Hadisinia *3
1- Medical Physics Dept, Ilam University of Medical Science, Ilam, Iran
2- Dept of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
3- Radiology Dept, School of Paramedical sciences, Guilan University of Medical Sciences, Rasht, Iran , sahebehs@yahoo.com
Abstract:   (25 Views)

Introduction:  Radiotherapy is one of the therapeutic options for malignancies associated with the abdominal cavity. However, the delivered dose must be limited to the kidneys' custom shielding blocks. This study aimed to propose a method in which kidney shielding blocks can be replaced with multi-leaf collimators (MLCs).
Materials & Methods: In the initial phase, both kidneys were protected, and the open field area was irradiated. However, the region between each kidney and the lateral abdominal wall was inevitably shielded. Therefore, in subsequent phases, the dose to the shielded region was necessarily compensated. This process was analyzed by treatment planning and Kodak EDR2 film dosimetry. The dosimetric film results, read with MATLAB, were compared with TPS data, showing a mean difference of less than 5%, indicating acceptable agreement between the two methods.
Results: The MLC-based shielding method demonstrated a noticeable reduction in treatment time compared to the time required for custom block fabrication and patient setup. The use of MLCs resulted in only a 3.86% increase in MU, which was not clinically significant. The mean dose to both kidneys in the MLC and cerrobend block methods remained within the renal tolerance limits. Furthermore, the consistency of average V10, V15, and V20 data for the left and right kidneys supported the agreement between the cerrobend block and MLC methods.
Conclusion: MLC application to the island organ as a shield is suggested, especially in AP/PA WAR. But sufficient accuracy in field matching is needed.

Keywords: MLC, Cerrobend block, WAR, kidney, Dosimetry
Full-Text [PDF 951 kb]   (8 Downloads)    
Type of Study: Research | Subject: Medical physics
Received: 2025/03/18 | Accepted: 2025/05/3 | Published: 2025/05/26
References
1. Dang YZ, Li X, Ma YX, Li XL, Yang T, Lu WL, et al. 18F FDG PET/CTguided intensity modulated radiotherapy for 42 FIGO III/IV ovarian cancer: A retrospective study. Oncol Lett. 2019;17:149-58. doi: 10.3892/ol.2018.9601.
2. Brady LW, Wazer DE, Perez CA. Perez & Brady's principles and practice of radiation oncology: Lippincott Williams & Wilkins; 2013.
3. Fields EC, McGuire WP, Lin L, Temkin SM. Radiation treatment in women with ovarian cancer: past, present, and future. Front Oncol. 2017;7:177. doi: 10.3389/fonc.2017.00177.
4. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin. 2019;69:7-34. doi: 10.3322/caac.21551.
5. Bentzen SM, Constine LS, Deasy JO. Quantitative analyses of normal tissue effects in the clinic (QUANTEC): an introduction to the scientific issues. Int J Radiat Oncol Biol Phys. 2010;76: S3–S9. doi: 10.1016/j.ijrobp.2009.09.040.
6. Committee ART, Boyer A. Basic applications of multileaf collimators: American Association of Physicists in Medicine Alexandria, VA; 2001.
7. Clarkson J. A note on depth doses in fields of irregular shape. Brit J Radio. 1941;14:265-8. doi: 10.1259/0007-1285-14-164-265.
8. Tajiri M, Sunaoka M, Fukumura A, Endo M. A new radiation shielding block material for radiation therapy: A shielding block made from a new material. Med Phys. 2004;31:3022-3. doi: 10.1118/1.1809767.
9. Boyer AL, Ochran TG, Nyerick CE, Waldron TJ, Huntzinger CJ. Clinical dosimetry for implementation of a multileaf collimator. Med Phys. 1992;19:1255-61. doi: 10.1118/1.596757.
10. LoSasso T, Chui CS, Ling CC. Physical and dosimetric aspects of a multileaf collimation system used in the dynamic mode for implementing intensity modulated radiotherapy. Med Phys. 1998;25:1919-27. doi: 10.1118/1.598381.
11. Fernandez E, Shentall G, Mayles W, Dearnaley D. The acceptability of a multileaf collimator as a replacement for conventional blocks. Radiother Oncol. 1995;36:65-74. doi: 10.1016/0167-8140(95)01571-w.
12. Antolak J. The Physics of Radiation Therapy. Wiley Online Library; 2015.
13. Goyal S, Osusky K, Gabel M, Yue NJ, Narra V. A Novel Method of Island Blocking in Whole Abdominal Radiotherapy Using a Modified Electronic Tissue Compensation Technique. Med Dosim. 2010;35:220-5. doi: 10.1016/j.meddos.2009.06.003.
14. Medicine AAoPi. Basic applications of multi-leaf collimators. AAPM Task Group. 2001;50.
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Parvaii W, Mehri-Kakavand G, Hadisinia T. Implementation of MLC-based techniques for kidney protection as isolated organs during radiotherapy of abdominal malignancies. J. Ilam Uni. Med. Sci. 2025; 33 (2) :1-12
URL: http://sjimu.medilam.ac.ir/article-1-8569-en.html


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Volume 33, Issue 2 (5-2025) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
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