Cardiac Troponin T Response during High-Intensity Competition 
and its Correlation with the Corrected QT Interval 
among the Trained Athletes

Kashef, Alireza; Shahidi, Fereshteh; Sadeghi Nikoo, Alireza

doi:10.29252/sjimu.28.2.1

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Volume 28, Issue 2 (5-2020)

Journal of Ilam University of Medical Sciences 2020, 28(2): 1-10

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Cardiac Troponin T Response during High-Intensity Competition and its Correlation with the Corrected QT Interval among the Trained Athletes

Alireza Kashef ^*

¹, Fereshteh Shahidi²

, Alireza Sadeghi Nikoo³

1- Dept of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Shahid Rajaee Teacher Training University, Tehran, Iran , kashefalireza@gmail.com
2- Dept of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Shahid Rajaee Teacher Training University, Tehran, Iran
3- Research and Sports Medicine Center of Oxygen Sports Group, Tehran, Iran

Abstract: (3585 Views)

Introduction: It is highly crucial to develop novel strategies in order to further enhance the monitoring of sudden cardiac arrest in athletes and establish standard medical care procedures to control monitoring and treatment costs. Therefore, this study aimed to investigate the effects of a high-intensity competition on cardiac troponin T (cTnT) and its correlation with the corrected QT interval (QTc) in the trained athletes.

Materials & Methods: In total, 32 male athletes (mean age: 26.9±4.7 years, body mass index: 25.6±1.6 kg/m²) competed in 8-min high intensity competitions. The competition items included running on skillmill for 400 meters; three-stage deadlifting, weight lifting (110kg) with 5 repetitions; (130kg) with 3 repetitions; and (150kg) with 1 repetition, bar pulling up with 30 repetition, 30-kg kettlebell swinging, and 20 sandbag throwing with different weights at a distance of 5m behind a 75-cm box. Moreover, lead II electrocardiogram was utilized in order to measure the resting QTc. The intravenous blood test was performed to determine the level of troponin T before and immediately after the competition. In addition, ANOVA with repeated measures was used to examine the differences between variables in resting position, post competition, and after correction for the volume of plasma lost. In addition, Bonferroni post hoc test was used to identify which mean differences were statistically significant. The Pearson Correlation Coefficient was calculated to assess the level of correlations between the variables and QTc. Ethics code: IR.SRTTU.SSF.2018.103

Findings: The results showed an immediate significant increase in the cardiac Troponin T after high-intensity competition, compared to the resting position (P<0.001). However, when raw post-exercise data were corrected for plasma volume loss, no significant difference was observed in this regard (F1,31= 832, P<0.001). Furthermore, the Pearson results indicated that there was no significant correlation between the resting QTc and cTnT before and after the high-intensity comoetition.

Discussion & Conclusions: There was no significant correlation between the QTc and cTnT among the trained atheletes after high-intensity competition. The QTc can not probably be ragrded as an independent high-risk predictor for myocardial damage and cTnT release in athletes. However, there is a need for more studies on athletes in different sports.

Keywords: Cardiac function, Electrocardiogram, Sudden cardiac death

Full-Text [PDF 1132 kb] (1474 Downloads)

Type of Study: Research | Subject: Physical Education
Received: 2019/06/5 | Accepted: 2020/01/11 | Published: 2020/06/30

References

1. Merghani A, Malhotra A, Sharma S. The U-shaped relationship between exercise and cardiac morbidity. Trend Cardiovasc Med2016;26:232-40. doi. 10.1016/j.tcm. 2015.06.005.

2. Carranzagarcia LE, George K, Serrano E, Casado R, Caballero AL, Legaz A. Cardiac biomarker response to intermittent exercise bouts. Int J Sport Med 2011;32:327-31. doi.10.1055/s-0030-1263138.

3. Kashef M, Yazdani F, Kashef A. [The survey of electrocardiogram alterations and vo2max of active male after consume caffeine with custo diagnostic]. Razi J Med Sci 2018;25:74-81.(Persian)

4. Chandra N, Bastiaenen R, Papadakis M, Sharma S. Sudden cardiac death in young athletes practical challenges and diagnostic dilemmas. J Am Coll Cardiol2013;61:1027-4. doi. 10.1016/j.jacc.2012.08.1032.

5. Kashef A, Ghazalian F, Shakeri N. [A Comparison of QTc among elite club and beginner male athletes at rest and in exhaustive exercise]. Sport Biosci2017;9: 431-41.(Persian)

6. Schmied C, Borjesson M. Sudden cardiac death in athletes. J Intern Med 2014;275:93-103. doi.10.1111/joim.12184.

7. Shave R, Baggish A, George K, Wood M, Scharhag J, Whyte G, et al. Exercise induced cardiac troponin elevation evidence mechanisms, and implications. J Am Coll Cardiol 2010;56:169-76. Doi. 10.1016.jacc. 2010.03.037.

8. Muthu V, Kozman H, Liu K, Smulyan H, Villarreal D. Cardiac troponins bench to bedside interpretation in cardiac disease. Am J Med Sci 2014;347:331-7. Doi. 10.1097/MAJ.0b013e31829107ea.

9. Ahmad MI. Biomarkers in acute myocardial infarction. J Clin Exp Cardiol2012; 3:213-8. doi.10.4172/2155-9880.1000222.

10. Wedin JO, Henriksson AE. Postgame elevation of cardiac markers among elite floorball players. Sca J Med Sci Sport2015;25:495-500. doi. 10.1111/sms.12304.

11. Klinkenberg LJ, Luyten P, Linden N, Urgel K, Snijders DP, Knackstedt C, et al. Cardiac troponin T and I release after a 30 km run. Am J Cardiol 2016;118:281-7. doi. 10.1016/j.amjcard.2016.04.030.

12. Duttaroy S, Thorell D, Karlsson L, Borjesson M. A single bout of one hour spinning exercise increases troponin T in healthy subjects. Sca Cardiovasc J2012;46:2-6. doi. 10.3109/14017431. 2011.622783.

13. Rajvanshi S, Nath R, Kumar M, Gupta A, Pandit N. Correlation of corrected QT interval with quantitative cardiac troponin-I levels and its prognostic role in Non ST elevation myocardial infarction. Int J Cardiol 2017;240:55-9. Doi. 10.1016/j.ijcard.2017.03.091.

14. Sugiura T, Dohi Y, Takase H, Fujii S, Ohte N. Findings relevant to the QRS wave in the resting electrocardiogram are associated with circulating concentrations of high sensitivity cardiac troponin I in the general population. J Am Soc Hyp 2018;12:614-20. doi. 10.1016/j.jash. 2018.05.003.

15. Bazett HC. AN analysis of the time relations of electrocardiograms. Ann Noninvasive Electrocardiol1997;2:177-94. doi.10.1111/j.1542-474X.1997.tb00325.x.

16. Dill DB, Costill DL. Calculation of percentage changes in volumes of blood plasma and red cells in dehydration. J Appl Physiol1974;37:247-8. doi. 10.1152/jappl. 1974.37.2.247.

17. Eijsvogels TM, Fernandez AB, Thompson PD. Are there deleterious cardiac effects of acute and chronic endurance exercise? Physiol Rev2016;96:99-125. doi. 10.1152/physrev.00029.2014.

18. Legaz A, Lopez I, George K, Puente JJ, Moliner D, Ayala VJ, et al. Individual variability in cardiac biomarker release after 30 min of high-intensity rowing in elite and amateur athletes. Appl Physiol Nutr Metab 2015;40:951-8. doi. 10.1139/apnm-2015-0055.

19. Pascal B, Sven Z, Rüdiger W, Frank CM, Andree H. Changes of Cardiac Biomarkers after High-intensity Exercise in Male and Female Elite Athletes of Dragon Boating. J Sport Sci2016;4:123-8. doi.10.17265/2332-7839/2016.01.001.

20. Savukoski T, Mehtala L, Lindahl B, Venge P, Pettersson K. Elevation of cardiac troponins measured after recreational resistance training. Clin Biochem 2015;48:803-6. doi.10.1016/j. clinbiochem. 2015.06,015.

21. Moonikh K, Kashef M, Kashef A. [The effect of different doses of caffeine on time to exhaustion and ventricular repolarization parameters at rest and immediately after the exhaustion in young men]. Nurse Phys With War2017;16:38-49.(Persian)

22. Lovic D, Narayan P, Pittaras A, Faselis C, Doumas M, Kokkinos P. Left ventricular hypertrophy in athletes and hypertensive patients. JCH 2017;19:413-7. doi:10.1111/jch.12977.

23. Nakamura M, Sadoshima J. Mechanisms of physiological and pathological cardiac hypertrophy. Nat Rev Cardiol2018;15:387-407. doi. 10.1038/s41569-018-0007-y.

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Kashef A, Shahidi F, Sadeghi Nikoo A. Cardiac Troponin T Response during High-Intensity Competition and its Correlation with the Corrected QT Interval among the Trained Athletes. J. Ilam Uni. Med. Sci. 2020; 28 (2) :1-10
URL: http://sjimu.medilam.ac.ir/article-1-5744-en.html

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