:: Volume 20, Issue 5 (3-2013) ::
Journal of Ilam University of Medical Sciences 2013, 20(5): 23-29 Back to browse issues page
Craniomaxillofacial bone tissue engineering: A review on growth factors
Sr Motamedian * 1, K Khosraviani , F Gholipour , P Gholamin , F Fili
1- , SR.Motamedian@yahoo.com
Abstract:   (11847 Views)
Currently autografts are gold standards for craniomaxillofacial bone regeneration. But autografts have some limitations. Bone tissue engineering has been introduced to overcome these limitations. It consist three components: stem cells, growth factor, and scaffold. Scaffold provides an environment for bone growth and simplifies cell adhesion, differentiation and proliferation. In this review, application of natural, synthetic and composite scaffolds in animal and human studies were described. Based on this review, autografts are still gold standards for bone regeneration. However, it seems that recent advances in technology of designing scaffolds would help designing more appropriate scaffolds for bone tissue engineering in near future.
Keywords: Tissue engineering, Bone regeneration, Scaffold, Stem cells, Craniomaxillofacial
Full-Text [PDF 368 kb]   (10546 Downloads)    
Type of Study: Research | Subject: Medical microbiology
Received: 2013/03/17 | Accepted: 2013/05/13 | Published: 2013/05/13

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Volume 20, Issue 5 (3-2013) Back to browse issues page