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Application of Phenols in Improvement of β-carotene as Anti-Cancer Agent Assisted by its UV Absorbing Quality
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M Entezari   , M Hekmati , S Heidari kashl * 1, A Azin , Sh Hekmat , A Barkat , R Shiri haris |
| 1- , saeed_heidari@spu.ir |
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Abstract: (15440 Views) |
| Introduction: The lifespan of organic coa-tings is reduced in outdoor applications by attacks of solar radiation, oxygen and atom-spheric pollutants. Degradation of coating and recoating introduce pollutants into the environment. For solvent based coatings like alkyd paints, volatile organic comp-ounds (VOC) are the main source of pollut-ion. Undesirable mechanical, physical and chemical consequences of the resulting degradation can be substantially restricted by properly selected photo stabilizers.
Materials & Methods: Carotene than carr-ots extracted by ethanol and 2 - propanol at a temperature of 60 º C in 4-2 hours. In this regard, samples and control were analyzed by UV spectroscopy and results were compared with samples after past 30 days exposure on the UV sunlight.
Findings: Beta carotene acts like a subs-tance against UV light and can increase the resistance of the material to be used as anticancer drug however it's not able to do the task by itself. In a view, beta carotene is counted as a powerful anti-oxidant material. If such material is increased in UVAs, the UV absorbing quality will be increased. Such work is considered a big advantage in anti-cancer drugs. Tautomerization and co-njugation in phenols makes them to be con-sidered as important UV absorbers and eff-ective class of UV-absorbers.
Discussion & Conclusion: In this paper we have investigated the effect of phenolic UVAs on increasing UV absorbing quality in beta carotene, viable cancer cell numbers or MTT test was also performed |
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| Keywords: phenol, MTT, UV Absorbing, β-carotene, anti-cancer |
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Full-Text [PDF 264 kb]
(2903 Downloads)
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Type of Study: Research |
Subject:
Molecular Genetics
Received: 2013/03/16 | Accepted: 2013/03/17 | Published: 2013/04/8
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