:: Volume 23, Issue 3 (9-2015) ::
Journal of Ilam University of Medical Sciences 2015, 23(3): 123-129 Back to browse issues page
The effects of intermittent hypoxia on plasma adiponectin level in obese people with type II diabetes
SARA Gharibshi * 1, Vahid Tadibi2 , Sakineh Nikseresht3 , Naser Behpoor2 , Dariush Sheikholeslami vatani3 , Ehsan Hoseinibidokhti2
1- Razi University , gharibshisara@gmail.com
2- Razi University
3- Kurdistan University
Abstract:   (7294 Views)

Introduction: Adiponectin is a hormone that plays an important role in diet-induced insulin resistance. People with higher weight have a lower adiponectin levels and are more susceptible to type II diabetes. Studies have shown that exposure to altitude and hypoxic environment causes weight loss. The aim of this study was to investigate the effect of intermittent hypoxia on adiponectin level and BMI in obese people with type II diabetes.
Materials and methods: Ten obese subjects with type II diabetes participate in the study with mean BMI of 32.02 ± 2.47 and age range of 50-70 years old. The intervention consisted of 14 sessions of intermittent hypoxia, one hour per day for 14 consecutive days. Plasma adiponectin and BMI were measured three times (pretest, day 7, and posttest) and two times (pre- and post-tests).
 Findings: Plasma adiponectin showed a non-significant 2.1% reduction, 6 days after intermittent hypoxia intervention (day 7) (t9= 1.06 p=0.317). Also, in fifteenth day or after 14 days of intermittent hypoxia intervention, plasma adiponectin levels had a 5% non-significant reduction compared to the pretest (t9= 0.578 p=0.577). The results of present study also showed that short-term (7 days) and medium term (14 days) exposure to intermittent hypoxia had no effect on BMI (p> 0.05).
 Discussion & Conclusion: Findings of present study indicate that performing 6 and 14 one-hour sessions of intermittent hypoxia in consecutive days cause no significant effect in plasma adiponectin and BMI of obese people with type II diabetes.

Keywords: Adiponectin, intermittent hypoxia, diabetic patients
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Type of Study: Research | Subject: physiology
Received: 2014/05/9 | Accepted: 2014/06/3 | Published: 2015/09/29

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Volume 23, Issue 3 (9-2015) Back to browse issues page