[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
About the Journal
Editorial Board
Aims& Scopes
Journal News
Articles archive::
All Issues
Current Issue
Browse by Authors
Browse by Keywords
Publication Ethics::
Peer Review Process::
Indexing Databases::
For Authors::
Authors Guideline
Call for Papers
Submission Instruction
Review Process
Research Ethics Statements
Ethical issues
Author Complaint Process
For Reviewers::
Reviewers Section
Subscription::
Registration Information
Subscription Form
Contact us::
Contact Information
Contact us
Site Facilities::
Site map
Search contents
FAQ
Top 10 contents
Inform to friends
::
Google Scholar Metrics

Citation Indices from GS

AllSince 2021
Citations83823846
h-index3120
i10-index24588
..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Registered in

AWT IMAGE

AWT IMAGE
..
:: Volume 34, Issue 2 (5-2026) ::
Journal of Ilam University of Medical Sciences 2026, 34(2): 32-40 Back to browse issues page
A rare case of preeclampsia associated with acrocyanosis and mild clubbing
Abbas Ghaysouri1 , Fariba Shokri1 , Reza Faraji *2
1- Tuberculosis and Lung Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran
2- Tuberculosis and Lung Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran , r.faraji61@gmail.com
Abstract:   (445 Views)
Introduction:  Preeclampsia is a severe pregnancy-related disorder characterized by hypertension and multi-organ damage. Along with hemorrhage and infection, it is one of the three leading causes of maternal mortality worldwide. The aim of this study was to report a case of preeclampsia accompanied by acrocyanosis and mild clubbing.
Case Report: In this study, a 32-year-old woman (G3P2) at 36 weeks of gestation presented with complaints of dyspnea, dizziness (particularly when lying in the left lateral position), intermittent nausea and vomiting, morning dryness of the lips and mouth, acrocyanosis, and mild clubbing. Her medical history was notable for two previous episodes of preeclampsia, prior cystocele surgery, previous rhinoplasty, and a weight gain of 12 kg over the preceding 1–2 months. Despite timely and appropriate therapeutic interventions, the patient remained hospitalized in the intensive care unit for 7 days with persistent acrocyanosis that did not improve despite oxygen therapy. She was subsequently discharged and referred to another center for magnetic resonance imaging (MRI).
Conclusion: This case highlights endothelial dysfunction induced by placental factors in preeclampsia, with particular emphasis on peripheral vascular manifestations such as acrocyanosis and clubbing. These findings underscore the importance of recognizing such signs as potential indicators of severe vascular involvement and suggest the need for further studies to evaluate their prevalence, pathophysiology, and prognostic significance in patients with preeclampsia.
 
Keywords: Preeclampsia, Acrocyanosis, Proteinuria
Full-Text [PDF 798 kb]   (196 Downloads)    
Editorial Note: case report | Subject: departmet of gynecology and obstetrics
Received: 2026/02/1 | Accepted: 2026/04/27 | Published: 2026/05/26
References
1. Yanga X, Jiachun Weic J, Lu Sunc L, Zhonga Q, Zhaia X, Chena Y, et al. Causal relationship between iron status and preeclampsia-eclampsia: a Mendelian randomization analysis. Clin Exp Hypertens. 2024; 46:2321148. doi: 10.1080/10641963.2024.2321148.
2. Jahan F, Vasam G, Cariaco Y, Nik-Akhtar A, Green A, Menzies KJ, et al. NAD+ depletion is central to placental dysfunction in an inflammatory subclass of preeclampsia. Life Sci Alliance. 2024;7: e202302505. doi: 10.26508/lsa.202302505.
3. Khalloufi C, Joudar I, Jalal M, Lamrissi A, Bouhya S. Atypical presentation of preeclampsia. Case report. Int J Surg Case Rep. 2023:103:107860. doi: 10.1016/j.ijscr.2022.107860.
4. Ahammedunni AE, Nour NB, Das K. Cesarean section in a morbidly obese patient with severe preeclampsia and pulmonary edema: A case report. Cureus. 2024;16: e65877. doi: 10.7759/cureus.65877.
5. Ge LP, Pan J, Liang M. Correlation analysis of maternal serum folate and 25(OH)D levels with the incidence of fetal growth restriction in patients with preeclampsia. J Matern Fetal Neonatal Med. 2024; 37:2400688. doi: 10.1080/14767058.2024.2400688.
6. Esercan A, Cindoglu C. The relationship between early-onset preeclampsia and the prognostic nutritional index and inflammatory markers. J Obstet Gynaecol. 2024; 44:2408680. doi: 10.1080/01443615.2024.2408680.
7. Li J, Kong Y, Shi G, Dong S, Wang X, Feng L, et al. Assessing the causal association of sleep abnormalities with preeclampsia and eclampsia: a Mendelian randomization analysis. Hypertens Pregnancy. 2024; 43:2405857. doi: 10.1080/10641955.2024.2405857.
8. Ives CW, Sinkey R, Rajapreyar I, Tita ATN, Oparil S. Preeclampsia-Pathophysiology and Clinical Presentations: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020; 76:1690-702. doi: 10.1016/j.jacc.2020.08.014.
9. Kornacki J, Wirstlein P, Wender-Ozegowska E. Markers of Endothelial Injury and Dysfunction in Early- and Late-Onset Preeclampsia. Life (Basel). 2020; 10:239. doi: 10.3390/life10100239.
10. Lecarpentier E, Tsatsaris V. Angiogenic balance (sFlt-1/PlGF) and preeclampsia. Ann Endocrinol (Paris). 2016; 77:97-100. doi: 10.1016/j.ando.2016.04.007.
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA

Ethics code: IR.MEDILAM.REC.1404.219

XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Ghaysouri A, Shokri F, Faraji R. A rare case of preeclampsia associated with acrocyanosis and mild clubbing. J. Ilam Uni. Med. Sci. 2026; 34 (2) :32-40
URL: http://sjimu.medilam.ac.ir/article-1-8893-en.html
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 34, Issue 2 (5-2026) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
Persian site map - English site map - Created in 0.16 seconds with 41 queries by YEKTAWEB 4766