1. Zatterale F, Longo M, Naderi J, Raciti GA, Desiderio A, Miele C, et al. Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes. Front Physiol. 2020;10:1607. doi: 10.3389/fphys.2019.01607.

2. Balistreri CR, Caruso C, Candore G. The role of adipose tissue and adipokines in obesity-related inflammatory diseases. Mediators Inflamm. 2010;2010:802078. doi: 10.1155/2010/802078.

3. Gerst F, Wagner R, Oquendo MB, Siegel-Axel D, Fritsche A, Heni M, et al. What role do fat cells play in pancreatic tissue? Mol Metab. 2019;25:1-10. doi: 10.1016/j.molmet.2019.05.001.

4. Al Jaberi S, Cohen A, D’Souza C, Abdulrazzaq YM, Ojha S, Bastaki S, et al. Lipocalin-2: Structure, function, distribution and role in metabolic disorders. Biomed Pharmacother. 2021;142:112002.

5. Wang Y, Lam KS, Kraegen EW, Sweeney G, Zhang J, Tso AW, et al. Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans. Clin Chem. 2007;53:34-41. doi: 10.1373/clinchem.2006.075614.

6. Yan QW, Yang Q, Mody N, Graham TE, Hsu CH, Xu Z, et al. The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance. Diabetes. 2007;56:2533-40. doi: 10.2337/db07-0007.

7. Roca-Rivada A, Castelao C, Senin LL, Landrove MO, Baltar J, Crujeiras AB, et al. FNDC5/irisin is not only a myokine but also an adipokine. PLoS One. 2013;8:e60563. doi: 10.1371/journal.pone.0060563.

8. Chen N, Li Q, Liu J, Jia S. Irisin, an exercise-induced myokine as a metabolic regulator: an updated narrative review. Diabetes Metab Res Rev. 2016;32:51-9. doi: 10.1002/dmrr.2660.

9. Palacios-González B, Vadillo-Ortega F, Polo-Oteyza E, Sánchez T, Ancira-Moreno M, Romero-Hidalgo S, et al. Irisin levels before and after physical activity among school-age children with different BMI: A direct relation with leptin. Obesity (Silver Spring). 2015;23:729-32. doi: 10.1002/oby.21029.

10. Belviranli M, Okudan N, Çelik F. Association of circulating irisin with insulin resistance and oxidative stress in obese women. Horm Metab Res. 2016;48:653-7. doi: 10.1055/s-0042-116155.

11. Arhire LI, Mihalache L, Covasa M. Irisin: a hope in understanding and managing obesity and metabolic syndrome. Front Endocrinol (Lausanne). 2019;10:524. doi: 10.3389/fendo.2019.00524.

12. Unamuno X, Gómez-Ambrosi J, Rodríguez A, Becerril S, Frühbeck G, Catalán V. Adipokine dysregulation and adipose tissue inflammation in human obesity. Eur J Clin Invest. 2018;48:e12997. doi: 10.1111/eci.12997.

13. Strasser B, Schobersberger W. Evidence for resistance training as a treatment therapy in obesity. J Obes. 2011; 2011:482564. doi:10.1155/2011/482564.

14. Görgens SW, Eckardt K, Jensen J, Drevon CA, Eckel J. Exercise and regulation of adipokine and myokine production. Prog Mol Biol Transl Sci. 2015;135:313-36. doi: 10.1016/bs.pmbts.2015.07.002.

15. Sakurai T, Izawa T, Kizaki T, Ogasawara Je, Shirato K, Imaizumi K, et al. Exercise training decreases expression of inflammation-related adipokines through reduction of oxidative stress in rat white adipose tissue. Biochem Biophys Res Commun. 2009; 379:605-9. doi: 10.1016/j.bbrc.2008.12.127. Epub 2009 Jan 1.

16. Shibata S, Hayakawa K, Egashira Y, Sanada H. Hypocholesterolemic mechanism of Chlorella: Chlorella and its indigestible fraction enhance hepatic cholesterol catabolism through up-regulation of cholesterol 7α-hydroxylase in rats. Biosci Biotechnol Biochem. 2007;71:916-25. doi: 10.1271/bbb.60566.

17. Lee HS, Kim MK. Effect of Chlorella vulgaris on glucose metabolism in Wistar rats fed high fat diet. J Med Food. 2009;12:1029-37. doi: 10.1089/jmf.2008.1269.

18. Rani K, Sandal N, Sahoo P. A comprehensive review on chlorella-its composition, health benefits, market and regulatory scenario. Pharma Innov J. 2018;7:584-9.

19. Sanayei M, Izadi A, Hajizadeh-Sharafabad F, Amirsasan R, Kaviani M, Barzegar A. Chlorella vulgaris in combination with high intensity interval training in overweight and obese women: a randomized double-blind clinical trial. J Diabetes Metab Disord. 2021;1-12. doi: 10.1007/s40200-021-00816-0.

20. Brzycki M. Strength testing—predicting a one-rep max from reps-to-fatigue. J Phys Educ Recreat Dance. 1993;64:88-90. doi: 10.1080/07303084.1993.10606684.

21. Ataeinosrat A, Saeidi A, Abednatanzi H, Rahmani H, Daloii AA, Pashaei Z, et al. Intensity dependent effects of interval resistance training on myokines and cardiovascular risk factors in males with obesity. Front Endocrinol. 2022;13:895512. doi: 10.3389/fendo.2022.895512.

22. Huang Y, Yang Z, Ye Z, Li Q, Wen J, Tao X, et al. Lipocalin-2, glucose metabolism and chronic low-grade systemic inflammation in Chinese people. Cardiovasc Diabetol. 2012;11:11. doi: 10.1186/1475-2840-11-11 .

23. Moschen AR, Adolph TE, Gerner RR, Wieser V, Tilg H. Lipocalin-2: a master mediator of intestinal and metabolic inflammation. Trends Endocrinol Metab. 2017;28:388-97. doi: 10.1016/j.tem.2017.01.003 .

24. Choi K, Kim T, Yoo H, Lee K, Cho G, Hwang T, et al. Effect of exercise training on A-FABP, lipocalin-2 and RBP4 levels in obese women. Clin Endocrinol (Oxf). 2009;70:569-74. doi: 10.1111/j.1365-2265.2008.03374.x.

25. Bonab SB, Dastah S. Performing training in water improves glucose homeostasis and lipocalins in women with type 2 diabetes mellitus. Sci Sports. 2022; 38-34-41. doi: 10.1016/j.scispo.2021.08.009.

26. Atashak S, Stannard SR, Daraei A, Soltani M, Saeidi A, Moradi F, et al. High-intensity interval training improves lipocalin-2 and Omentin-1 levels in men with obesity. Int J Sports Med. 2022;43:328-35. doi: 10.1055/a-1560-5401. Epub 2021 Oct 12.

27. Sabzevari F, Mogharnasi M, Golestani F. Effect of 6 weeks Pilates training along with dill supplementation on serum concentrations of nesfatin-1, lipocalin-2, and insulin resistance in females with overweight and obesity: a randomized controlled trial. J Res Med Sci. 2022;27:59. doi: 10.4103/jrms.JRMS_612_20.

28. Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012;481:463-8. doi: 10.1038/nature10777.

29. Aydin S, Kuloglu T, Aydin S, Eren MN, Celik A, Yilmaz M, et al. Cardiac, skeletal muscle and serum irisin responses to with or without water exercise in young and old male rats: cardiac muscle produces more irisin than skeletal muscle. Peptides. 2014;52:68-73. doi: 10.1016/j.peptides.2013.11.024.

30. Kraemer R, Shockett P, Webb N, Shah U, Castracane V. A transient elevated irisin blood concentration in response to prolonged, moderate aerobic exercise in young men and women. Horm Metab Res. 2014;46:150-4. doi: 10.1055/s-0033-1355381. Epub 2013 Sep 23.

31. Qiu S, Cai X, Sun Z, Schumann U, Zuegel M, Steinacker JM. Chronic exercise training and circulating irisin in adults: a meta-analysis. Sports Med. 2015;45:1577-88. doi: 10.1007/s40279-014-0293-4.

32. Parada-Sánchez SG, Macias-Cervantes MH, Pérez-Vázquez V, Vargas-Ortiz K. The effects of different types of exercise on circulating irisin levels in healthy individuals and in people with overweight, metabolic syndrome and type 2 diabetes. Physiol Res. 2022;71: 457-75 doi: 10.33549/physiolres.934896.

33. Kazeminasab F, Sadeghi E, Afshari-Safavi A. Comparative impact of various exercises on circulating irisin in healthy subjects: a systematic review and network meta-analysis. Oxid Med Cell Longev. 2022; 2022:8235809. doi: 10.1155/2022/8235809.

34. Ghanbari-Niaki A, Saeidi A, Ahmadian M, Gharahcholo L, Naghavi N, Fazelzadeh M, et al. The combination of exercise training and Zataria multiflora supplementation increase serum irisin levels in postmenopausal women. Integr Med Res. 2018;7:44-52. doi: 10.1016/j.imr.2017.12.004 .

35. Zhang Y, Li R, Meng Y, Li S, Donelan W, Zhao Y, et al. Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling. Diabetes. 2014;63:514-25. doi: 10.2337/db13-0887.