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:: Volume 18, Issue 3 (10-2010) ::
sjimu 2010, 18(3): 69-78 Back to browse issues page
A Study of Human Respiratory Syncytial Virus Genotypes in Children Less Than 5 Years of Age with Acute Respiratory Symptoms in 2007 and 2009
Abstract:   (11726 Views)
Introduction: Human respiratory syncytial virus (HRSV) is the most important viral agent of acute respiratory infection in children less than 5 years age worldwide. HRSV is responsible for 50% brochiolitis and 25% pneumonia in infants. There are limited data of HRSV genotypes from developing countries. The aim of this study was to investigate HRSV genotypes in 2007 and 2009 in Iran. Materials & Methods: 72 and 107 respiratory samples were collected from children less than 5 years of age with acute respiratory infection in 2007and 2009, respectively, whom were tested for G glycoprotein gene of HRSV by RT-PCR. Findings: Of the 72 respiratory samples tested in 2007, 14 samples (19,44%) were positive for HRSV and fell on three genotypes: 12 strains in GA2, 1 strain in GA1 , and 1strain in GA5. Whereas, of the 107 respiratory samples tested in 2009, 24 samples (22,24%) were positive that 16 (67%) belonged to subgroup A genotypes: 15 strains in GA1, and 1Strain in GA2, whereas, 8 (33%) clustered in genotype BA in subgroup B. Discussion & Conclusion: This study revealed that multiple genotypes of HRSV were cocirculated on years 2007 and 2009 in Iran. Also our results showed that subgroup A strains were more prevalent than subgroup B viruses, GA2 and GA1 genotypes were predominant genotypes on years 2007 and 2009, respectively.
Keywords: Keywords: human respiratory syncytial virus, genotype, acute respiratory infection
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Type of Study: Research | Subject: General
Received: 2011/03/15 | Accepted: 2015/04/8 | Published: 2015/04/8
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A Study of Human Respiratory Syncytial Virus Genotypes in Children Less Than 5 Years of Age with Acute Respiratory Symptoms in 2007 and 2009. sjimu. 2010; 18 (3) :69-78
URL: http://sjimu.medilam.ac.ir/article-1-245-en.html


Volume 18, Issue 3 (10-2010) Back to browse issues page
مجله علمی پزوهشی دانشگاه علوم پزشکی ایلام scientific journal of ilam university of medical sciences
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