TY - JOUR JF - sjimu JO - J. Ilam Uni. Med. Sci. VL - 21 IS - 3 PY - 2013 Y1 - 2013/8/01 TI - The histological effects of chronic multiple sequential stress on rat testis TT - اثرات استرس مزمن چندگانه بر ساختار بافتی بیضه موش صحرایی N2 - Background: The increase of stress following the technological improvements appears to be an important factor that causes organs disorders like genital system. Therefore the present study was conducted to investigate the effects of chronic multiple sequential stress on rat testis Methods: 18 Wistar rats were divided randomly into two equal groups. In animals under stress, the mice were exposed to different multiple sequential stress as Forced swimming, Restraint, Water deprivation, Isolation and Food deprivation for 10 days while the animals in control group were kept in their cages without any disorders. After weighing the animals and anesthesing with xylazine-Ketamine, the testis of animals were removed and weighed. After fixation with formaldehyde (10%), testis samples were prepared for light microscopic study. The number of spermatogonia, spermatocytes I & II, sperm & leydig cells, thickness of the seminiferous tubule determined using Image Tool software in the studied groups. Finally the data were compared statistically. Results: The present study showed that the mean number of spermatogonia، spermatocyte I & II، sperm & leydig cells in stress group have significantly decreased compared to control group (P SP - 83 EP - 90 AU - fard, Maryam AU - Rajaei, Farzad AU - Sarokhani, Mohammad-Reza AD - Qazvin University Of Medical Sciences KW - chronic multiple sequential stress KW - seminiferous tubule KW - spermatogonia KW - sperm KW - leydig KW - rat UR - http://sjimu.medilam.ac.ir/article-1-714-en.html ER -