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Review of Enterotoxigenic Escherichia coli bacteria vaccines
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R Khalesi   , J Salimian *1 , Sm Moazeni , F Azizi jalilian |
| 1- , jafarsalimyan@yahoo.com |
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Abstract: (14282 Views) |
| Enterotoxigenic Escherichia coli is the most common bacterial agent producing diarrhea in the world wide. This bacterium includes some virulence factors such as colonization factors and heat-labile toxin and/ or heat-stable toxin. Enterotoxigenic Escherichia coli attached to the intestinal epithelial cell surface through CFs and causes diarrhea by toxin secretion. Molecular pathogenesis stu-dies demonstrate that there are many pro-phylactic approaches for this infection. The best possible way is designing and prod-ucing efficient vaccine that enabeling to induc protective immunity against the most of bacterial strains. Vaccine candidate molecule(s) that are used to design a vaccine, in addition to possess immuno-genicity and safety they should be wid-espread among variety of strains and co-ntain conserved and common epitops. This article pays attention to review some infor-mation and results of conducted researches on enterotoxigenic Escherichia coli vaccine and importance of the bacteria and its pathogenesis. |
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| Keywords: enterotoxigenic escherichia coli, pathogenesis, vaccine, virulence factors |
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Full-Text [PDF 371 kb]
(19515 Downloads)
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Type of Study: Research |
Subject:
Medical microbiology
Received: 2013/03/17 | Accepted: 2013/10/15 | Published: 2013/10/15
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