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Effects of Alcea angulata Root Alcoholic Extract on Blood Lipid of Male Rabbit
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Z Fahimi *   1, J Cheraghi , AA Pilehvarian , K Sayehmiri , A Khosravi |
| 1- , zeinab_fahimi@yahoo.com |
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Abstract: (12633 Views) |
| Introduction: Concerning hyperlipidemia as one of the most important risk factors of cardiovascular diseases, this study pegs at examining effect of alcoholic extracts of root of Alcea Angulata on lipid profile of serum in hyperlipidemic rabbits.
Materials & Methods: After two weeks, 25 New Zealand white male rabbits were divided into five groups randomly each group included 5 rabbits. They were treated with 1% cholesterol, basic diet, 1% cholesterol, and intervention diet (root of Alcea angulata with 200, 400, and 800 mg/kg body weight) respectively, for one month. In the end of 30-day period, all the fasting rabbits were blood sampled and their lipid profiles of serum were detected.
Findings: Serum level of total cholesterol and LDL.c of treated groups by Alcea angulata were lower than that in the control meaningfully, (P<0.01) likewise, serum level of HDL in treated groups by Alcea angulata was higher than that in the control group meaningfully, (P<0.01). These values varied with dose amounts.
Discussion & Conclusion: Based on findings of this study, lipids percentage of hyperlipidemic rabbits' serum was declined after consuming alcoholic extracts of Alcea Angulata. Hereby, Alcea angulata would be regareded as a helpful treatment for hyperlipidemia |
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| Keywords: Alcea angulata, hyperlipidemia, rabbit |
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Full-Text [PDF 1057 kb]
(4036 Downloads)
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Type of Study: Research |
Subject:
General
Received: 2012/08/11 | Published: 2012/08/15
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