:: Volume 23, Issue 1 (4-2015) ::
Journal of Ilam University of Medical Sciences 2015, 23(1): 134-142 Back to browse issues page
Oxidative Stress, Cancer and Obesity, Three Complications Threatens Health in Down Syndrome that Are Preventable
Seyyed Mostafa Nachvak1 , Kurosh Djafarian * 2
1- Kermanshah University of
2- tehran University of Medical Sciences , kdjafarian@tums.ac.ir
Abstract:   (7298 Views)

Down syndrome as the most common chromosome abnormality, and the most common cause of mental retardation in human societies, is responsible for over one-third of learning disorders. Children with Down syndrome are usually smaller in size compared to other children, and their mental and physical development stages are slower than their peers. This syndrome has different symptoms including major or minor abnormalities in the structure or function of body’s organs. Incidence of some disorders that can be serious health threats, such as oxidative stress, cancer and obesity in patients with Down syndrome are more common than other people in community. This paper meanwhile describes the mechanisms of incidence of these complications, also refers to some points about prevention and reduction of their pathogenesis.

Keywords: Down syndrome, Oxidative stress, Cancer, Obesity
Full-Text [PDF 495 kb]   (2131 Downloads)    
Type of Study: Research | Subject: biochemistry and nutrition
Received: 2014/04/22 | Accepted: 2014/06/10 | Published: 2015/05/18


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Volume 23, Issue 1 (4-2015) Back to browse issues page