Introduction: Actually, food sanitation is a guarantee of proper food quality and it is an essential pillar in health promoting of community. The aim of this study was to study of knowledge and attitude among Ilam University of medical sciences students regarding to food sanitation and safety on 2013.
 Material and method: 430 Ilam University of medical sciences students was determined in present cross-sectional study by stratified random sampling. Data collected through a questionnaire consisting of three parts including personal information, knowledge and attitudes towards food sanitation and safety. The data were used by SPSS16 software and analyzed by Mann- Whitney and kruskal-wallis tests.
 Findings: overall, results showed that 3.5% of students had good attitude, 77.6% moderate attitude and 18.5% poor attitude. In the field of knowledge 18.5 % had adequate knowledge, 16.2% moderate knowledge and 2.4% poor knowledge about food sanitation. Results showed that there is a significant relation between students' attitudes regarding food sanitation and safety and their sex (p = .036), and also there isaa significant relation between knowledge (p = .000) and attitude (p = .048) of students and passing the food sanitation course.
Discussion&Conclusion: It is proposed that according to relation between knowledge, food sanitation and safety, educational programs to be held in the form of workshops or incorporate food sanitation courses for fields of medical science that does not pass this course.