:: Volume 21, Issue 6 (12-2013) ::
Journal of Ilam University of Medical Sciences 2013, 21(6): 134-145 Back to browse issues page
X-linked Hyper-IgM Syndrome: Control and Treatment
A Khalil nejad , E Mahmodian , A Khalil nejad , R Roghanian , A Etedali , R Vafaee * 1, M Hosainzade
1- , Vafaeereza@gmail.com
Abstract:   (13460 Views)
X-linked hyper-IgM syndrome (XHIGM) is a congenital immunodeficiency in which the immune system cannot produces differ-rent classes of immunoglobulins other than IgM. Therefore, the patients are susceptible to many disorders, infectious diseases and malignancies. Bone marrow or allogeic he-matopoietic cell sorcord blood stem cells transplantation are the two accepted ther-apeutic approaches to treat patients with XHIGM. In addition, various numbers of interventions including IVIG and SCIG therapy, antimicrobial agents and etcare used to control and prevent the XHIGM-related diseases and conditions. In the present manuscript, we review all of these approaches.
Keywords: anaphylaxis, antibody therapy, bone marrow transplantation, primary imm-uneodeficiency, stem cell transplantation
Full-Text [PDF 383 kb]   (5597 Downloads)    
Type of Study: Research | Subject: immunology
Received: 2014/01/4 | Accepted: 2014/01/4 | Published: 2014/01/4

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Volume 21, Issue 6 (12-2013) Back to browse issues page