1. Farag YM, Gaballa MR. Diabesity an overview of a rising epidemic. Nephrol Dial Transplant 2011;26:28-35. doi.10.1093/ndt/gfq576.

2. Liu Q, Wang S, Cai L. Diabetic cardiomyopathy and its mechanisms: role of oxidative stress and damage. J Diabetes Investig 2014;5:623-34. doi.10.1111/jdi.12250.

3. Wang J, Song Y, Elsherif L, Song Z, Zhou G, Prabhu SD, et al. Cardiac metallothionein induction plays the major role in the prevention of diabetic cardiomyopathy by zinc supplementation. Circulation 2006; 113:544-54. doi:10.1161/circulationaha.105.537894.

4. Abdi A, Ramezani N, Abbasidaloie A, Ganji N. [The effect of aerobic training and coriandrum sativum extract on some oxidative stress factors in male diabetic wistar Rats]. Tabari J Prev Med 2017; 2:34-43. (Persian).

5. Ji L, Gomez M, Steinhafel N, Vina J. Acute exercise activates nuclear factor NF-κB signaling pathway in rat skeletal muscle. FASEB J 2004;18:1499-506. doi.10.1096/fj.04-1846com.

6. Ghyasi R, Mohaddes G, Naderi R. Combination effect of voluntary exercise and garlic (Allium sativum) on oxidative stress, cholesterol level and histopathology of heart tissue in type 1 diabetic Rats. J Cardiovasc Thorac Res 2019;11:61. doi.10.15171/jcvtr.2019.10.

7. Naderi R, Mohaddes G, Mohammadi M, Ghaznavi R, Ghyasi R, Vatankhah AM. Voluntary exercise protects heart from oxidative stress in diabetic Rats. Adv Pharm Bull 2015;5:231. d doi.10.15171/apb.2015.032.

8. Farzanegi P, Habibian M, Anvari SM. [Effect of swimming training and arbutin supplement on cardiac antioxidant enzymes and oxidative stress in diabetic Rats]. J Gorgan Uni Med Sci 2015;17:39-45. (Persian)

9. Judge S, Jang YM, Smith A, Selman C, Phillips T, Speakman JR, et al. Exercise by lifelong voluntary wheel running reduces subsarcolemmal and interfibrillar mitochondrial hydrogen peroxide production in the heart. Am J Physiol Reg Int Comp Physiol 2005;289: 1564-72. doi.10.1152/ajpregu.00396.2005.

10. Kazaz IO, Mentese A, Demir S, Kerimoglu G, Colak F, Bodur A, et al. Berberine inhibits the ischemia-reperfusion induced testicular injury through decreasing oxidative stress. Am J Eme Med 2020;38:33-37. doi.10.1016/j.ajem.2019.04.001.

11. Zhao GL, Yu LM, Gao WL, Duan WX, Jiang B, Liu XD, et al. Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress. Acta Pharmacol Sin 2016;37:354-67. doi.10.1038/aps.2015.136.

12. Yu L, Li Q, Yu B, Yang Y, Jin Z, Duan W, et al. Berberine attenuates myocardial ischemia/reperfusion injury by reducing oxidative stress and inflammation response: role of silent information regulator 1. Oxid Med Cell Long 2016;2016:1689602. doi.10.1155/2016/1689602.

13. Seo H, Park CH, Choi S, Kim W, Jeon BD, Ryu S. Effects of voluntary exercise on apoptosis and cortisol after chronic restraint stress in mice. J Exerc Nutrition Biochem 2016;20:16. doi.10.20463/jenb.2016.09.20.3.3.

14. Høydal MA, Wisloff U, Kemi OJ, Ellingsen O. Running speed and maximal oxygen uptake in rats and mice: practical implications for exercise training. Eur J Cardiovasc Prev Rehabil 2007;14:753-60. doi: 10.1097/HJR.0b013e3281eacef1.

15. Mahmoud AM, Abdelrahman MM, Bastawy NA, Eissa HM. Modulatory effect of berberine on adipose tissue PPARγ, adipocytokines and oxidative stress in high fat diet/streptozotocin-induced diabetic Rats. JAPS 2017;7: -10. doi.10.7324/JAPS.2017.70401.

16. Servais S, Couturier K, Koubi H, Rouanet J, Desplanches D, Sornay M, et al. Effect of voluntary exercise on H2O2 release by subsarcolemmal and intermyofibrillar mitochondria. Free Rad Biol Med 2003;35:24-32. doi.10.1016/s0891-5849(03)00177-1.

17. Leeuwenburgh C, Hansen PA, Holloszy JO, Heinecke JW. Oxidized amino acids in the urine of aging rats: potential markers for assessing oxidative stress in vivo. Am J Physiol 1999;276: 128-35. doi: 10.1152/ajpregu.

18. Gimenes C, Gimenes R, Rosa C, Xavier N, Campos D, Fernandes A, et al. Low intensity physical exercise attenuates cardiac remodeling and myocardial oxidative stress and dysfunction in diabetic rats. J Diabetes Res 2015; 2015:457848. doi.10.1155/2015/457848.

19. Ghiasi R, Naderi R, Mozaffar A, Alihemmati A. The effect of swimming training on oxidative stress SIRT1 gene expression and histopathology of hepatic tissue in type 2 diabetic Rats. Biol Futura 2019; 70:167-74. doi.10.1556/019.70.2019.21.

20. Farhangi N, Nazem F, Zehsaz F. [Effect of endurance exercise on antioxidant enzyme activities and lipid peroxidation in the heart of the streptozotocin induced diabetic Rats]. JSSU 2017;24:798-809. (Persian)

21. Heyat F. [Cellular and Molecular Mechanisms of the production of free radicals during exercise and their function on skeletal muscles]. J Fasa Uni Med Sci 2017;7:1-11. (Persian)

22. Steinbacher P, Eckl P. Impact of oxidative stress on exercising skeletal muscle. Biomolecules 2015;5:356-77. doi.10.3390/biom5020356.

23. Toborek M, Seelbach MJ, Rashid CS, András IE, Chen L, Park M, et al. Voluntary exercise protects against methamphetamine induced oxidative stress in brain microvasculature and disruption of the blood brain barrier. Mole Neurodegener 2013; 8:22. doi.10.1186/1750-1326-8-22.

24. Kulkarni SK, Dhir A. Possible involvement of L-arginine-nitric oxide cyclic guanosine monophosphate signaling pathway in the antidepressant activity of berberine chloride. Eur J Pharmacol 2007;569:77-83. doi.10.1016/j.ejphar.2007.05.002.

25. Ju H, Li X, Zhao B, Han Z, Xin W. Scavenging effect of berbamine on active oxygen radicals in phorbol ester stimulated human polymorphonuclear leukocytes. Biochem Pharmacol 1990;39:1673-8. doi.10.1016/0006-2952(90)90110-7.

26. Kong WJ, Zhang H, Song DQ, Xue R, Zhao W, Wei J, et al. Berberine reduces insulin resistance through protein kinase C–dependent up regulation of insulin receptor expression. Metabolism 2009;58:109-19. doi.10.1016/j.metabol.2008.08.013.

27. Sharma B, Salunke R, Balomajumder C, Daniel S, Roy P. Anti-diabetic potential of alkaloid rich fraction from Capparis decidua on diabetic mice. J Ethnopharmacol 2010;127:457-62. doi.10.1016/j.jep.2009.10.013.

28. Zhang X, Ren H, Liu L. Effects of different dose berberine on hemodynamic parameters and Ca2+ i of cardiac myocytes of diastolic heart failure Rat model. Zhong Yao Za Zhi 2008;33:818-21.

29. Tan Y, Tang Q, HU Br, Xiang JZ. Antioxidant properties of berberine on cultured rabbit corpus cavernosum smooth muscle cells injured by hydrogen peroxide 1. Acta Pharmacol Sin 2007;28:1914-8. doi.10.1111/j.1745-7254.2007. 00705.x

30. Ezabadi A, Peeri M, Azarbayjani MA, Hosseini SA. The effects of resistance training and berberine chloride supplementation on oxidative stress markers in the cerebellum tissue of diazinon poisoned Rats. Middle East J Rehabil Health Stud20013; 6: 92870. doi.10.5812/mejrh.92870.